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Table 1 Contrast of the clinicopathology of LCC, LCNEC-null and LCNEC

From: Pulmonary large cell carcinoma with neuroendocrine morphology shows genetic similarity to large cell neuroendocrine carcinoma

 

LCC

LCNEC-null

LCNEC

(n = 7)

(n = 11)

(n = 13)

Median age

61 (41–68)

64 (48–73)

57 (42–78)

Sex

 Male

7

11

12

 Female

–

–

1

Smoking history

 smoker

7

8

12

 non-smoker

–

3

1

 Tumour size (cm)

7.5 ± 2.5

5.1 ± 3.2

6.8 ± 4.8

 Lymph node metastasis

4 (57.1%)

3 (27.3%)

5 (38.5%)

Stage

 I

–

3

5

 II

2

3

1

 III / IV

5

5

7

 Pleural invasion

3 (42.8%)

3 (27.3%)

6 (46.2%)

Color of cut surface

 Yellow / Brown

6 (85.7%)

3 (27.3%)

3 (23.0%)

 White

1 (14.3%)

8 (72.7%)

7 (53.8%)

 Other

–

–

3 (23.0%)

Tumour texture

 Soft

5 (71.4%)

–

–

 Middle

2 (28.6%)

7 (63.6%)

10 (76.9%)

 Hard

–

4 (36.4%)

2 (15.4%)

  1. LCC, large cell carcinoma; LCNEC-null, large cell neuroendocrine carcinoma-null immunophenotype; LCNEC, large cell neuroendocrine carcinoma