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Fig. 2 | Diagnostic Pathology

Fig. 2

From: Cyclin D1 and PRAME expression in distinguishing melanoma in situ from benign melanocytic proliferation of the nail unit

Fig. 2

Representative clinical morphology, photomicrographs of H&E staining, and IHC staining for cyclin D1 and PRAME of selected subunugal melanoma in situ. One 44-year-old patient (A) 2 mm-wide melanonychia showed (B) atypical melanocyte proliferation with confluency and pagetoid spread (200x magnification, H&E). Both (C) cyclin D1 and (D) PRAME IHC showed over 90% nuclear immunostaining (200x magnification, respectively), (E) Sox-10 IHC (200x magnification)

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Diagnostic Pathology

ISSN: 1746-1596

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