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Fig. 2 | Diagnostic Pathology

Fig. 2

From: Dual block HER2 assessment increased HER2 immunohistochemistry positive rate in resected specimens of gastric cancer: a prospective multicenter clinical trial from China

Fig. 2

Comparison of HER2 IHC positive rate based on gender, age, tumor location, differentiation, Lauren classification, and stage. HER2 3+ rate was slightly higher in male than in female (*P = 0.113). The rate elevated with the increase of age (#P = 0.038). Higher positivity was found in GCs that located in the OGJ/U, and lower positive rate was shown in tumors that located in M/L (^P = 0.001). Low-grade tumors (well/moderate differentiation) and intestinal tumors were with higher HER2 positivity (¶P < 0.001). Stage did not affect the HER2 3+ rate (&P = 0.317). Abbreviations: Intestinal: Intestinal type; Diffuse: Diffuse type; Mixed: Mixed type; Indeterminate: Indeterminate type; OGJ: Oesophagogastric junction; U: The upper third of the stomach; M: The middle third of the stomach; L: The lower third of the stomach.

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