Skip to main content
Fig. 5 | Diagnostic Pathology

Fig. 5

From: Mixed neuroendocrine-non-neuroendocrine neoplasm of the gallbladder: case report and literature review

Fig. 5

Case 1: Immunohistochemical staining findings for LCNEC and adenocarcinoma. a Syn staining was diffuse and strongly positive in LCNEC and negative in adenocarcinoma. Magnification, × 40. b Staining for CgA was weakly positive in LCNEC and negative in adenocarcinoma area. Magnification, × 40. c High Ki67 proliferation index was found in LCNEC and the adenocarcinoma component. Magnification, × 40. d AE1/AE3 staining was strongly positive in adenocarcinoma, and punctate weak positive staining was observed in LCNEC. Magnification, × 40. e TP53 staining showed overexpression in the LCNEC component (left) and in the adenocarcinoma component (upper right). Magnification, × 40. f TP53 staining also showed overexpression in the adenocarcinoma component (> 80%). Magnification, × 40

Back to article page

Diagnostic Pathology

ISSN: 1746-1596

Contact us