Table 1 Clinicopathologic characteristics of patients by EBV status
Clinicopathologic parameters | IBC tissue EBER-ISH | ||
|---|---|---|---|
Positive | Negative | P-value | |
age | 0.705 | ||
≤ 50 | 15 (37.5%) | 25(62.5%) | |
>50 | 42(42.0%) | 58(52.0%) | |
tumor size | 0.043 | ||
≤ 2.0 cm | 28 (33.7%) | 55 (66.3%) | |
> 2.0 cm | 29 (50.9%) | 28 (49.1%) | |
Menopausal status | < 0.01 | ||
postmenopausal | 22 (23.7%) | 71 (76.3%) | |
menstruating | 35 (74.5%) | 12 (25.5%) | |
Histological subtype | 0.302 | ||
IDC | 48 (42.9%) | 64 (57.1%) | |
ILC | 9 (32.1%) | 19 (67.9%) | |
Histological classification of IDC | 0.22 | ||
I | 7 (24.1%) | 22 (75.9%) | |
II | 15 (42.9%) | 20 (57.1%) | |
III | 26 (54.2%) | 22 (45.8%) | |
Nodal metastasis | < 0.01 | ||
Present | 37 (59.7%) | 25 (40.3%) | |
Absent | 20 (25.6%) | 58 (74.4%) | |
Lymphovascular Invasion | < 0.01 | ||
Present | 31 (72.1%) | 12 (27.9%) | |
Absent | 26 (26.8%) | 71 (73.2%) | |
Ki-67 Index | 0.006 | ||
<14% | 7 (21.2%) | 26(78.8%) | |
>14% | 50(57.1%) | 57(53.3%) | |
TNM Clinical Stage | < 0.01 | ||
I ~ II | 19 (19.4%) | 79 (80.6%) | |
III ~ IV | 38 (90.5%) | 4 (9.5%) | |
ER | 0.05 | ||
Positive | 25(30.5%) | 57(69.5%) | |
Negative | 32(55.2%) | 26(44.8%) | |
PR | 0.09 | ||
Positive | 7 (15.2%) | 26 (84.8%) | |
Negative | 50(46.7%) | 57(53.3%) | |
HER-2 | 0.078 | ||
Positive | 20(54.1%) | 17(45.9%) | |
Negative | 37(35.6%) | 66(64.4) | |