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Fig. 1 | Diagnostic Pathology

Fig. 1

From: A retrospective analysis of serous effusions based on the newly proposed international system for reporting serous fluid cytopathology: a report of 3633 cases in an oncological center

Fig. 1

False-positive cases in pleural effusion specimens. Case 1: The cytological diagnosis was ‘SFM (IVa)’ (A, HE, × 400), while the histological diagnosis was granulomatous lesions (B, HE, × 200). We think that the epithelioid cells in the granulomatous lesions (bottom right of the Figure B) may have been mistaken for SFM. Case 2: The cytological diagnosis was ‘SFM (IVa)’ (C, HE, × 100), while the clinical diagnosis was ‘tuberculosis’. The patient had a history of abdominal lymphoma. A few weeks after the cytological diagnosis, he was clinically diagnosed with thoracic tuberculosis, and the pleural fluid disappeared after anti-tuberculosis treatment. The history of lymphoma may have led to our incorrect diagnosis. Case 3: The cytological diagnosis was ‘SFM (IVa)’ (D, Papanicolaou stain, × 400), while the clinical diagnosis was ‘chylothorax’. The misdiagnosed cells may be reactive mesothelial cells caused by chylothorax

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