Skip to main content

Table 4 The performance analysis among different serous effusions in current study and previous publications

From: A retrospective analysis of serous effusions based on the newly proposed international system for reporting serous fluid cytopathology: a report of 3633 cases in an oncological center

   

Positive standard

MAL + SFM + AUS

MAL + SFM

MAL

Pleural effusions

Current study

Sensitivity

88.5%

86.5%

62.0%

  

Specificity

92.4%

99.4%

100.0%

  

PPV

97.5%

99.8%

100.0%

  

NPV

70.2%

68.3%

43.5%

  

Diagnostic accuracy

89.4%

89.4%

70.6%

 

Previous publications

Sensitivity

-

60.3%-99.7% [11, 13]

61.6%-87% [10, 11, 14, 16]

  

Specificity

-

98.6%-99.4% [11, 13]

93.3%-100% [10, 11, 14, 16]

  

PPV

-

96.5%-98.3% [11, 13]

96.2%-100% [10, 11, 14, 16]

  

NPV

-

79.2%-99.9% [11, 13]

56%-98% [10, 11, 14, 16]

  

Diagnostic accuracy

-

97% [11]

81.3%-98% [10, 11, 14, 16]

Peritoneal effusions

Current study

Sensitivity

90.0%

88.4%

63.7%

  

Specificity

96.0%

99.6%

100.0%

  

PPV

98.8%

99.9%

100.0%

  

NPV

72.5%

70.3%

43.2%

  

Diagnostic accuracy

91.3%

90.8%

71.6%

 

Previous publications

Sensitivity

-

-

61.2% [10]

  

Specificity

-

-

100.0% [10]

  

PPV

-

-

100.0% [10]

  

NPV

-

-

70.0% [10]

  

Diagnostic accuracy

-

-

79.7% [10]

Pericardial effusions

Current study

Sensitivity

89.7%

89.7%

73.1%

  

Specificity

100.0%

100.0%

100.0%

  

PPV

100.0%

100.0%

100.0%

  

NPV

82.6%

82.6%

64.4%

  

Diagnostic accuracy

93.1%

93.1%

81.9%

 

Previous publications

Sensitivity

-

-

97%-100% [10, 16]

  

Specificity

-

-

100% [10, 19]

  

PPV

-

-

100% [10, 19]

  

NPV

-

-

99%-100% [10, 16]

  

Diagnostic accuracy

-

-

99%-100% [10, 16]

Total effusions

Current study

Sensitivity

89.0%

87.2%

62.9%

  

Specificity

93.8%

99.5%

100.0%

  

PPV

98.0%

99.8%

100.0%

  

NPV

71.4%

69.5%

44.1%

  

Diagnostic accuracy

90.1%

90.0%

71.3%

 

Previous publications

Sensitivity

23.5%-100% [15]

  

Specificity

66.2%-100% [15]

  

PPV

87.0%-100% [15]

  

NPV

19.1%-100% [15]

  

Diagnostic accuracy

 

-

 
  1. Abbreviations: AUS atypia of undetermined significance, SFM suspicious for malignancy, MAL malignancy, PPV positive predictive value, NPV negative predictive value
Back to article page

Diagnostic Pathology

ISSN: 1746-1596

Contact us