Fig. 4

Detection of cell nuclei using the region-based convolutional neural network method. Epoch 1 indicates the start of learning, while epoch 40 indicates the end of learning 40 times. Epoch 1 can identify the parts other than the cell nuclei (A), red cell nuclei (B), and blue absent cell nuclei (C). Learning allowed the discrimination of the blue-tinted nuclei alone (D, E, F), and the discrimination performance was improved