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Fig. 3 | Diagnostic Pathology

Fig. 3

From: Expression of immune checkpoint regulators, programmed death-ligand 1 (PD-L1/PD-1), cytotoxic T lymphocyte antigen 4 (CTLA-4), and indolaimine-2, 3-deoxygenase (IDO) in uterine mesenchymal tumors

Fig. 3

CTLA-4 and IDO reactions in Leiomyosarcoma. H&E stain of a case of primary leiomyosarcoma showing pleomorphic malignant cells (case# 17, Additional Table 1). The corresponding CTLA-4 and IDO IHC stains show positive granular cytoplasmic staining of the malignant cells. (40 × objective). Abbreviations: H&E, hematoxylin & eosin; CTLA-4, cytotoxic T lymphocyte antigen 4; IDO, indolaimine-2, 3-deoxygenase; IHC, immunohistochemistry

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