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Fig. 3 | Diagnostic Pathology

Fig. 3

From: Comprehensive genomic profiling of a unique liposarcoma arising in a patient with Li–Fraumeni syndrome and the novel detection of c-myc amplification: a case report

Fig. 3

A FISH analysis using a Vysis LSI MYC Dual Color Break Apart Rearrangement Probe (Catalog Number: 5J9101, Abott, US) did not show break-apart signals of c-myc, but an increased number of c-myc signals (red: 5′ myc, green: 3′ myc). B FISH analysis using a Vysis LSI IGH/MYC CEP 8 Tri-color Dual Fusion Translocation Probe (Catalog Number: 5J7501, Abott, US) did not show fusion signals of c-myc-IGH, but an increased number of c-myc signals (red: c-myc, arrow head, green: 14q32, arrow, blue: 8 cen). C FISH analysis using a c-myc/CEN8p Dual Color FISH probe (Product Number: GC009, GSP Lab., Inc., Japan) showed amplification signals of c-myc (red: c-myc, green: CEN8p)

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Diagnostic Pathology

ISSN: 1746-1596

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