Skip to main content

Table 6 Immunohistochemical staining patterns according to the TP53 mutation types in MDM2-amplified cases

From: p53 immunostaining pattern is a useful surrogate marker for TP53 gene mutations

TP53 mutation types

Immunohistochemical pattern of p53

Overexpression

Null type

Usual

IF-DBD

2 (66.7)

0 (0)

0 (0)

DISDRUPTED

0 (0)

1 (100)

0 (0)

Wild type

1 (33.3)

0 (0)

8 (100)

Total

3

1

8

  1. The corresponding percentages are shown in parentheses