From: p53 immunostaining pattern is a useful surrogate marker for TP53 gene mutations
TP53 mutation types | Immunohistochemical pattern of p53 | ||
---|---|---|---|
Overexpression | Null type | Usual | |
IF-DBD | 2 (66.7) | 0 (0) | 0 (0) |
DISDRUPTED | 0 (0) | 1 (100) | 0 (0) |
Wild type | 1 (33.3) | 0 (0) | 8 (100) |
Total | 3 | 1 | 8 |