Table 2 Clinicopathological characteristics of reported cases of MM with smooth muscle cell differentiation (Including Current Case)
Reference | Age/Sex | Sites | Cell morphology | Pigment | Melanocyctic markers | Other markers | Differentiation |
|---|---|---|---|---|---|---|---|
Banerjee et al. 1996 [11] | 54/F | The epigastric area and right axillary lymph node metastasis, the subcutaneous tissue of the left upper back, right inguinal nodes metastasis and metastasis around the iliac vessels | Plump spindle cells, polygonal cells and large numbers of multinucleated tumour giant cells | Absent | S100+, HMB-45- | a-SMA+, Desmin+, HHF-35+ | Smooth muscle |
Ul-Mulk et al. 2012 [12] | 73/F | Right arm, right axillary nodes and multiple metastases to the liver, lung, breast and skin | Composed of two different contiguous morphological, respectively melanosomes and leiomyosarcoma | Present | S100+, Melan A+ | a-SMA+, Desmin+ | Smooth muscle |
Morimoto et al. 2014 [13] | 63/F | The left toe and left groin lymph node metastasis | The neoplasm was composed of pleomorphic spindle cells | Absent | S100+, MITF-1+, HMB-45+ | a-SMA+, Desmin+ | Smooth muscle |
Prieto-Torres et al. 2017 [14] | 69/F | The left scapular area | The tumor cells with rhabdoid and spindle morphology | Absent | S100+, SOX10+, Melan A-, HMB-45- | a-SMA+, Desmin+ | Smooth muscle |
Current case | 54/M | The right nasal cavity | Epithelioid/rhabdoid and spindle cells | Present | S100+, SOX10+, Melan A+, HMB-45+, PNL2+ | a-SMA+, Desmin+, Caldesmon+, Cloponin+ | Smooth muscle |