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Fig. 4 | Diagnostic Pathology

Fig. 4

From: Clinicopathological features and genomic profiles of a group of secretory breast carcinomas in which progressive cases have more complex genomic features

Fig. 4

Summary of next-generation sequencing results for 6 lesions in 4 secretory carcinoma patients. All lesions demonstrated ETV6–NTRK3 gene fusion by DNA sequencing. Patient 2 sequencing results showed DOT1L, KDM5A, LRP1B variants in primary lesions and TERT and STAT3 mutation variants in recurrent lesions, except for the same ETV6-NTRK3 gene fusion sites. Patient 3 had two ETV6-NTRK3 gene fusion sites, and PGR gene variation was detected.

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Diagnostic Pathology

ISSN: 1746-1596

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