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Fig. 5 | Diagnostic Pathology

Fig. 5

From: SNHG15 enhances cisplatin resistance in lung adenocarcinoma by affecting the DNA repair capacity of cancer cells

Fig. 5

SNHG15 enhances DDP resistance in LUAD mouse model. A Size of tumors in BALB/C mice with different treatments. 1: sh-NC; 2: sh-SNHG15; 3: sh-NC + DDP; 4: sh-SNHG15 + DDP. B Tumor size measured every 4 days after different treatments; C Weight of mouse tumors after different treatments. D SNHG15 expression assessed through qRT-PCR with different treatments. E IHC assay was performed to determine the expression of ECE2 and γH2AX with different treatments. F Apoptosis in tumor sections measured through TUNEL assay (scale bar: 100 µm), and the mean gray value indicated the degree of apoptosis. (* indicates P < 0.05)

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