Preoperative and intraoperative assessment of myometrial invasion in patients with FIGO stage I non-endometrioid endometrial carcinoma—a large-scale, multi-center, and retrospective study

Table 3 Cronbach’s α—inter rate correlation, Kappa value, accuracy, sensitivity, specificity, PPV, NPV of the methods used for assessing myometrial invasion compared with the final paraffin-embedded pathology evaluation

MI	PS of postoperative pathology			Cronbach’s α	Kappa	Accuracy % (95% CI)	Sensitivity % (95% CI)	Specificity % (95% CI)	PPV % (95% CI)	NPV % (95% CI)
MI	No	Yes	Total	Cronbach’s α	Kappa	Accuracy % (95% CI)	Sensitivity % (95% CI)	Specificity % (95% CI)	PPV % (95% CI)	NPV % (95% CI)
CT
No	4	25	29	0.350	0.118	50.00 (35.72- 64.28)	45.65 (31.18- 60.84)	100.00 (39.58–100.00)	100.00 (80.76–100.00)	13.79 (4.51- 32.57)
Yes	0	21	21
Total	4	46	50
MRI
No	12	43	55	0.247	0.131	69.35 (62.11- 75.78)	73.13 (65.45- 79.68)	46.15 (27.14- 66.25)	89.31 (82.41- 93.82)	21.82 (12.25- 35.36)
Yes	14	117	131
Total	26	160	186
IGE
No	19	49	68	0.483	0.303	82.40 (77.85- 86.21)	84.24 (79.60- 88.01)	63.33 (43.90- 79.45)	95.97 (92.70- 97.87)	27.94 (18.06- 40.34)
Yes	11	262	273
Total	30	311	341
IFS
No	8	7	15	0.780	0.631	93.04 (86.33- 96.73)	93.40 (86.40- 97.08)	88.89 (50.67- 99.42)	99.00 (93.76- 99.95)	53.33 (27.42- 77.72)
Yes	1	99	100
Total	9	106	115

IFS Intraoperative frozen section, MRI Magnetic resonance imaging, CT Computerized tomography, MI Myometrial invasion, IGE Intraoperative gross examination, PS Paraffin section