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Table 3 Distribution characteristics of HR-HPVRNAscope expression patterns for different CIN lesions in the control group

From: CIN grades possessing different HPV RNA location patterns and RNAscope is helpful tool for distinguishing squamous intraepithelial lesions in difficult cervical cases

RNAscope + 

CIN1(n = 16)

CIN2(n = 15)

CIN3(n = 18)

χ2

P valuea

BME + 

0/16(0)

1/15(6.7%)

2/18(11.1%)

1.831

0.4

FTE + 

3/16(18.8%)

13/15(86.7%)

16/18(88.9%)

22.745

 < 0.001

SLE + 

16/16(100%)

14/15(93.3%)

1/18(5.6%)

40.92

 < 0.001

  1. BME Basal to mid-epithelium, FTE Full thickness epithelium, SLE Superficial layer epithelium
  2. achi-square test
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Diagnostic Pathology

ISSN: 1746-1596

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