Table 5 Differential diagnosis
Clinical manifestations | CD19 | CD20 | CD22 | CD79a | PAX-5 | CD163 | CD68 | CD4 | CD56 | Lysozyme | TIA-1 | CD45(LCA) | TdT | S-100 | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Diffuse large B-cell lymphoma | NS | + | + | + | + | + | NA | NA | NA | NA | NA | NA | NA | NA | NA |
Histiocytic sarcoma | Fever, weight loss, rash or hepatosplenomegaly, decreased eosinophil count. | – | – | – | NA | NA | + | + | + | + | Gorky District + | – | + | – | + |
Blastic plasmacytoid dendritic-cell tumor | Skin lesions (nodules, plaques, or abrasions), thrombocytopenia | – | – | NA | – | NA | NA | + | + | + | NA | NA | + | + | + |
Primitive monocytic sarcoma | NS | – | – | NA | – | – | – | + | + | + | + | Scattered + | – | – | – |