Diagnostic performance of Idylla MSI test in colorectal cancer biopsies

Diagnostic Pathology

Table 1 Characteristics of the four discrepant CRC biopsy cases between MMR IHC and Idylla MSI test

Case	Tumor site	Tumor type	Tumor cell% pre/post Idylla	Tumor area mm²	MMR IHC	Idylla 1st analysis	Idylla 2nd analysis*
C19	Left	NOS	15/10	25	dMLH1/PMS2	MSS	MSS
C38	Left	partim mucinosum	30/10	25	dMLH1/PMS2	MSS	MSS
C40	Left	signet ring cell	50/40	25	dMSH2/dMSH6	MSS	MSI
C70	Right	signet ring cell	5/5	25	dMLH1/PMS2	MSS	MSS

*2nd analysis was performed with an increased number of formalin-fixed paraffin-embedded sections.
Colorectal cancer (CRC), Mismatch repair (MMR), Microsatellite instable (MSI), Microsatellite stable (MSS), Not otherwise specified (NOS).

ISSN: 1746-1596