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Table 2 Diagnostic accuracy of Twist-1 expression in CM and PM in cut-off value 50% for villous stromal cells and 10% for syncytiotrophoblasts

From: Pathogenic role of Twist-1 protein in hydatidiform molar pregnancies and investigation of its potential diagnostic utility in complete moles

Ā 

Complete mole

Partial mole

Sensitivity

Specificity

Positive predictive value

Negative predictive value

Stromal cells

-Moderate to strong staining in >ā€‰50% of cells

-Weak staining in <ā€‰50%

42

5

10

30

89.5%

75.0%

80.7%

85.7%

Syncytiotrophoblasts

-Negative or weak staining in <ā€‰10% of cells

-Moderate or strong staining in >ā€‰10% of cells

39

8

16

24

82.9%

60.0%

70.9%

75.0%