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Fig. 1 | Diagnostic Pathology

Fig. 1

From: Synchronous thyroid cancer and malignant struma ovarii: concordant mutations and microRNA profile, discordant loss of heterozygosity loci

Fig. 1

Malignant Struma Ovarii. A Low power view (0.4x) of H&E section from the left ovary shows thyroid follicles of various sizes and shapes embedded in an inflamed fibrotic stroma. Note the malignant aggregate of thyroid tissue (circled) and adjacent poorly formed thyroid follicles (arrow). B High power image (20x) of the malignant component with nuclear pleomorphism, nuclear overlapping, irregular nuclear contour, and nuclear pseudoinclusions (arrow). These cells are positive for TTF-1 (C) and thyroglobulin (D). Magnification in panel C and D is demonstrated by a scale bar

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Diagnostic Pathology

ISSN: 1746-1596

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