Table 2 The list of gene sets

ERS-related genes

ACADVL, ADD1, AGR2, ARFGAP1, ATP6V0D1, BAK1, BAX, BCL2L11, BFAR, COPS5, CTDSP2, CUL7, CXXC1, DAB2IP, DCTN1, DDRGK1, DDX11, DNAJB11, DNAJB9, DNAJC3, EDEM1, ERN1, ERN2, EXTL1, EXTL2, EXTL3, FICD, FKBP14, GET3, GFPT1, GOSR2, GSK3A, HDGF, HSPA5, HYOU1, KDELR3, KLHDC3, LMNA, MYDGF, PARP16, PDIA5, PDIA6, PLA2G4B, PPP2R5B, PREB, PTPN1, SEC31A, SERP1, SHC1, SRPRA, SRPRB, SSR1, SULT1A3, SULT1A4, SYVN1, TATDN2, TLN1, TMEM33, TPP1, TSPYL2, UFL1, VAPB, WFS1, WIPI1, XBP1, YIF1A, ZBTB17, ASNS, ATF3, ATF4, ATF6, CCL2, CEBPB, CEBPG, CXCL8, DCP2, DDIT3, DIS3, EXOSC1, EXOSC2, EXOSC3, EXOSC4, EXOSC5, EXOSC6, EXOSC7, EXOSC8, EXOSC9, HERPUD1, IGFBP1, KHSRP, NFYA, NFYB, NFYC, PARN, ATF6B, CALR, HSP90B1, MBTPS1, MBTPS2

Check-point genes

IDO1, LAG3, CTLA4, TNFRSF9, ICOS, CD80, PDCD1LG2, TIGIT, CD70, TNFSF9, ICOSLG, KIR3DL1, CD86, PDCD1, LAIR1, TNFRSF8, TNFSF15, TNFRSF14, IDO2, CD276, CD40, TNFRSF4, TNFSF14, HHLA2, CD244, CD274, HAVCR2, CD27, BTLA, LGALS9, TMIGD2, CD28, CD48, TNFRSF25, CD40LG, ADORA2A, VTCN1, CD160, CD44, TNFSF18, TNFRSF18, BTNL2, C10orf54, CD200R1, TNFSF4, CD200, NRP1