Fig. 4

Solid neoplasm with vascular channels encircled by normal liver parenchyma (N) of well-defined borders (a). The lesion shows pseudovascular patterns with abundant lymphocytes, perivascular eosinophils, and epithelioid cells (b). Tumor-associated lymphohistiocytic infiltrate (c). Thick-wall vessels and dilated vascular channels with thin septae hosting tumoral cells (d). Detail of neoplastic “PEComatous” epithelioid cells of large nuclei neighboring vascular areas (circle) (e). Positive HMB-45 immunoexpression of tumor cellularity (f)