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COVID-19 and impact on peer review

As a result of the significant disruption that is being caused by the COVID-19 pandemic we are very aware that many researchers will have difficulty in meeting the timelines associated with our peer review process during normal times.  Please do let us know if you need additional time. Our systems will continue to remind you of the original timelines but we intend to be highly flexible at this time.

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  1. Sudden cardiac death resulting from acute myocardial infarction (AMI) constitutes a significant percentage of the caseload for forensic and clinical pathologists. When sudden death occurs at an early stage (<6...

    Authors: Haitao Bi, Ying Yang, Jianye Huang, Yingmin Li, Chunling Ma and Bin Cong
    Citation: Diagnostic Pathology 2013 8:84
    Content type: Research Published on:

  2. As glioma ranks as the first most prevalent solid tumors in primary central nervous system, certain single-nucleotide polymorphisms (SNPs) may be related to increased glioma risk, and have implications in carc...

    Authors: Gang Li, Tianbo Jin, Hongjuan Liang, Zhiguo Zhang, Shiming He, Yanyang Tu, Haixia Yang, Tingting Geng, Guangbin Cui, Chao Chen and Guodong Gao
    Citation: Diagnostic Pathology 2013 8:83
    Content type: Research Published on:

  3. It has been accepted that reversed halo sign (RHS) appeared on a computed tomography (CT) image in immunocompromised patients indicates an invasive fungal infection, but its pathophysiology remains obscure as ...

    Authors: Yoichiro Okubo, Takao Ishiwatari, Haruka Izumi, Fumitomo Sato, Kyoko Aki, Daisuke Sasai, Tsunehiro Ando, Minoru Shinozaki, Kazuhiko Natori, Naobumi Tochigi, Megumi Wakayama, Yoshinobu Hata, Haruo Nakayama, Tetsuo Nemoto and Kazutoshi Shibuya
    Citation: Diagnostic Pathology 2013 8:82
    Content type: Case Report Published on:

  4. D cyclins positively regulate the cell cycle and mediate the pathogenesis of some lymphomas. Cyclin D1 overexpression is the hallmark of mantle cell lymphoma, whereas cyclins D2 and D3 are reportedly not as sp...

    Authors: Takuro Igawa, Yasuharu Sato, Katsuyoshi Takata, Noriko Iwaki, Takehiro Tanaka, Naoko Asano, Yoshinobu Maeda, Yorihisa Orita, Naoya Nakamura, Shigeo Nakamura and Tadashi Yoshino
    Citation: Diagnostic Pathology 2013 8:81
    Content type: Research Published on:

  5. The differential diagnosis between primary and secondary breast cancers might be difficult, especially in poorly differentiated tumors. Thyroid Transcription Factor-1 (TTF-1) has been regarded as a reliable ma...

    Authors: Tor A Klingen, Ying Chen, PÃ¥l Suhrke, Ingunn M Stefansson, Marian D Gundersen and Lars A Akslen
    Citation: Diagnostic Pathology 2013 8:80
    Content type: Research Published on:

  6. The virtual slide(s) for this article can be found here: http://​www.​diagnosticpathol​ogy.​diagnomx.​eu/​vs/​1955868163936338​

    Authors: Haidong Huang, Chen Li, Chong Bai, Qiang Li, Weiqiang Zheng, Zhi Zhu, Paul Zarogoulidis, Konstantinos Zarogoulidis, Andreas Gschwendtner, Wolfgang Hohenforst-Schmidt and Michael Simoff
    Citation: Diagnostic Pathology 2013 8:79
    Content type: Case Report Published on:

  7. Congenital generalized lipodystrophy (CGL) also known as Berardinelli-Seip Congenital Lipodystrophy (BSCL) is a genetically heterogeneous disorder characterized by loss of adipose tissues, Acanthosis nigricans...

    Authors: Obaid Ur Rahman, Nadeem Khawar, Muhammad Aman Khan, Jawad Ahmed, Kamran Khattak, Jumana Yousuf Al-Aama, Muhammad Naeem and Musharraf Jelani
    Citation: Diagnostic Pathology 2013 8:78
    Content type: Research Published on:

  9. With varied immunohistochemistry scoring criteria and patient cohorts, HER2-positivity rates in gastric cancer (GC) and gastroesophageal junction (GEJ) adenocarcinoma have been reported with a wide range. Rece...

    Authors: Ling Shan, Jianming Ying and Ning Lu
    Citation: Diagnostic Pathology 2013 8:76
    Content type: Research Published on:

  10. A mammary nodular lesion was recognized one month before the surgery in the right upper breast of a 55-year-old female. The fine needle aspiration cytology specimens contained many individual bizarre, multi-nu...

    Authors: Sohsuke Yamada, Atsunori Nabeshima, Yoshika Nagata, Takashi Tasaki, Hirotsugu Noguchi, Shohei Kitada, Satoshi Kimura, Ke-Yong Wang, Shohei Shimajiri and Yasuyuki Sasaguri
    Citation: Diagnostic Pathology 2013 8:75
    Content type: Case Report Published on:

  11. Carcinosarcoma of the uterine cervix is less common than its counterpart in the uterine corpus. On the other hand, mesonephric adenocarcinoma is also a rare neoplasm in the uterine cervix, and it has been repo...

    Authors: Shiori Meguro, Masanori Yasuda, Michio Shimizu, Akira Kurosaki and Keiichi Fujiwara
    Citation: Diagnostic Pathology 2013 8:74
    Content type: Case Report Published on:

  12. Sudden death from an undiagnosed primary intracranial neoplasm is an exceptionally rare event, with reported frequencies in the range of 0.02% to 2.1% in medico-legal autopsy series and only 12% of all cases o...

    Authors: Irene Riezzo, Rosanna Zamparese, Margherita Neri, Francesco De Stefano, Ruggero Parente, Cristoforo Pomara, Emanuela Turillazzi, Francesco Ventura and Vittorio Fineschi
    Citation: Diagnostic Pathology 2013 8:73
    Content type: Case Report Published on:

  14. Small breast epithelial mucin (SBEM) has been implicated in tumor genesis and micrometastasis in breast cancer. Triple-negative breast cancer (TNBC) was characterized by high incidence in young women,early rel...

    Authors: Liang Liu, Zhaozhe Liu, Shuxian Qu, Zhendong Zheng, Yongye Liu, Xiaodong Xie and Fulin Song
    Citation: Diagnostic Pathology 2013 8:71
    Content type: Research Published on:

  16. Accumulating evidence for differential expression of microRNA-224 (miR-224) in various types of human cancer suggests that it may be play a crucial role in tumor biology. The previous microarray detection also...

    Authors: Shu-na Shen, Ling-feng Wang, Yong-feng Jia, Yu-qing Hao, Lin Zhang and Hui Wang
    Citation: Diagnostic Pathology 2013 8:69
    Content type: Research Published on:

  17. An imbalance between pro-oxidants and antioxidant systems has been suggested to be implicated in the physiopathology of acute myocardial infarction (AMI). We aimed to evaluate the antioxidant capacity in Tunis...

    Authors: Yosri Noichri, Abdelkader Chalghoum, Latifa Chkioua, Bruno Baudin, Samia Ernez, Salima Ferchichi and Abdelhédi Miled
    Citation: Diagnostic Pathology 2013 8:68
    Content type: Research Published on:

  18. The WHO classification system for astrocytomas is not considered optimal, mainly because of the subjective assessment of the histopathological features. Few prognostic variables have been found that stratify t...

    Authors: Tove Lind-Landström, Rosilin K Varughese, Stein Sundstrøm and Sverre H Torp
    Citation: Diagnostic Pathology 2013 8:67
    Content type: Research Published on:

  19. Primary angiosarcoma of the breast is extremely rare. Radiologic findings are often non specific and may appear completely normal in one-third of cases with primary angiosarcoma. The prognosis is usually poor ...

    Authors: Amal Bennani, Layla Chbani, Meryem Lamchahab, Mouhcine Wahbi, Fatimazzahra Fdili Alaoui, Ikram Badioui, Moulay Abdelilah Melhouf and Affaf Amarti
    Citation: Diagnostic Pathology 2013 8:66
    Content type: Case Report Published on:

  20. In the WHO 2010 classification, the neuroendocrine tumors (NETs) are subdivided by their mitotic index or Ki67 index into either G1 or G2 NETs. Tumors with a Ki67 index of <2% are classified as G1 and those wi...

    Authors: Takeshi Yamaguchi, Takahiro Fujimori, Shigeki Tomita, Kazuhito Ichikawa, Hiroyuki Mitomi, Kazuya Ohno, Yosuke Shida and Hiroyuki Kato
    Citation: Diagnostic Pathology 2013 8:65
    Content type: Research Published on:

  22. Composite pheochromocytoma/paraganglioma is a rare tumor with elements of pheochromocytoma/paraganglioma and neurogenic tumor. Most were located in the adrenal glands, and extra-adrenal composite pheochromocyt...

    Authors: Jinchen Hu, Jitao Wu, Li Cai, Lei Jiang, Zhiqiang Lang, Guimei Qu, Houcai Liu, Weidong Yao and Guohua Yu
    Citation: Diagnostic Pathology 2013 8:63
    Content type: Case Report Published on:

  24. The fine balance of Th17/Treg is crucial for maintenance of immune homeostasis. The objective of this study was to investigate the balance of Th17/Treg and the expression of related cytokines in Uighur cervica...

    Authors: Zhifang Chen, Jianbing Ding, Nannan Pang, Rong Du, Wei Meng, Yuejie Zhu, Yi Zhang, Cailing Ma and Yan Ding
    Citation: Diagnostic Pathology 2013 8:61
    Content type: Research Published on:

  26. Diagnosing Plasmodium falciparum malaria during pregnancy is a great challenge for clinicians because of the low density of parasites in the peripheral blood and parasite sequestration in the placenta. Neverthele...

    Authors: Awadalla H Kashif, Gamal K Adam, Ahmed A Mohmmed, Salah E Elzaki, Ahmed M AbdelHalim and Ishag Adam
    Citation: Diagnostic Pathology 2013 8:59
    Content type: Research Published on:

  27. Identifying novel tumor biomarkers to develop more effective diagnostic and therapeutic strategies for patients with ACC is urgently needed. The aim of the study was to compare the proteomic profiles between a...

    Authors: Ming-shan Yang, Huan-sheng Wang, Bao-sheng Wang, Wan-hu Li, Zeng-fen Pang, Ben-kui Zou, Xin Zhang, Xue-tao Shi, Dian-bin Mu, De-xian Zhang, Yong-sheng Gao, Xiao-wen Sun and Shu-jie Xia
    Citation: Diagnostic Pathology 2013 8:58
    Content type: Research Published on:

  28. Surveillance after orchiectomy has recently been a management option in patients with stage I seminoma, while it remains controversial in those with stage I nonseminoma, and the risk factor associated with rel...

    Authors: Kazuhiro Kobayashi, Toshihiro Saito, Yasuo Kitamura, Tomohiro Nobushita, Takashi Kawasaki, Noboru Hara and Kota Takahashi
    Citation: Diagnostic Pathology 2013 8:57
    Content type: Research Published on:

  29. Apart from a number of cases of inaccurate prognosis in regard to individual patients, the inter- and intra-observer variability of the classical, histological prognosis parameters have been under repeated dis...

    Authors: Klaus-Jürgen Winzer, Joachim Bellach and Peter Hufnagl
    Citation: Diagnostic Pathology 2013 8:56
    Content type: Research Published on:

  30. Skewed X-chromosome inactivation (SXCI) was found in some apparently healthy females mainly from Western countries. It has been linked to development of ovarian, breast and pulmonary carcinomas. The present st...

    Authors: Gang Li, Tianbo Jin, Hongjuan Liang, Yanyang Tu, Wei Zhang, Li Gong, Qin Su and Guodong Gao
    Citation: Diagnostic Pathology 2013 8:55
    Content type: Research Published on:

  31. Abetalipoproteinemia (ABL; OMIM 200100) is a rare monogenic disorder of lipid metabolism characterized by reduced plasma levels of total cholesterol (TC), low density lipoprotein-cholesterol (LDL-C) and almost...

    Authors: Mohamed Najah, Sarraj Mohamed Youssef, Hrira Mohamed Yahia, Slimani Afef, Jelassi Awatef, Hammami Saber, Najjar Mohamed Fadhel, Agnès Sassolas and Slimane Mohamed Naceur
    Citation: Diagnostic Pathology 2013 8:54
    Content type: Research Published on:

  32. A 45-year-old female patient was referred to our hospital for complaining of dyspnea and coughing in the past four months. The computed tomography scanning demonstrated a central lesion in the upper lobe of th...

    Authors: Juan-Han Yu, Xu-Yong Lin, Liang Wang, Yang Liu, Chui-Feng Fan, Yong Zhang and En-Hua Wang
    Citation: Diagnostic Pathology 2013 8:53
    Content type: Case Report Published on:

  35. Nodular fasciitis is the most common pseudosarcomatous lesion of soft tissue. Ki67 was considered as a useful marker for distinguishing some benign and malignant lesions. To study the usefulness of Ki67 in dia...

    Authors: Xu-Yong Lin, Liang Wang, Yong Zhang, Shun-Dong Dai and En-Hua Wang
    Citation: Diagnostic Pathology 2013 8:50
    Content type: Research Published on:

  37. The comparative study of the results of various segmentation methods for the digital images of the follicular lymphoma cancer tissue section is described in this paper. The sensitivity and specificity and some...

    Authors: Anna Korzynska, Lukasz Roszkowiak, Carlos Lopez, Ramon Bosch, Lukasz Witkowski and Marylene Lejeune
    Citation: Diagnostic Pathology 2013 8:48
    Content type: Research Published on:

  39. Saliva and sweat are modified by cystic fibrosis (CF). In both cases the chloride and sodium ion concentrations for healthy subjects and CF patients differ, this representing a possible alternative tool for CF...

    Authors: Aline Cristina Gonçalves, Fernando Augusto de Lima Marson, Regina Maria de Holanda Mendonça, José Dirceu Ribeiro, Antonio Fernando Ribeiro, Ilma Aparecida Paschoal and Carlos Emílio Levy
    Citation: Diagnostic Pathology 2013 8:46
    Content type: Research Published on:

  40. Gastric cancer is one of the most common malignant tumors in the world. Finding effective diagnostic biomarkers in urine or serum would represent the most ideal solution to detecting gastric cancer during annu...

    Authors: Xueyan Dong, Guoqing Wang, Guoqing Zhang, Zhaohui Ni, Jian Suo, Juan Cui, Ai Cui, Qing Yang, Ying Xu and Fan Li
    Citation: Diagnostic Pathology 2013 8:45
    Content type: Research Published on:

  41. The differential diagnosis between metastatic head & neck squamous cell carcinomas (HNSCC) and lung squamous cell carcinomas (lung SCC) is often unresolved because the histologic appearance of these two tumor ...

    Authors: Anita Lal, Rebecca Panos, Mira Marjanovic, Michael Walker, Eloisa Fuentes, Gregory J Kubicek, W David Henner, Ljubomir J Buturovic and Meredith Halks-Miller
    Citation: Diagnostic Pathology 2013 8:44
    Content type: Research Published on:

  42. Aggressive natural killer cell leukemia/lymphoma (ANKL) is a rare aggressive form of NK-cell neoplasm. We report an uncommon case of 36-year-old male who showed jaundice and spontaneous splenic rupture. The di...

    Authors: Li-min Gao, Wei-ping Liu, Qun-pei Yang, Hui-fang Li, Jun-jie Chen, Yuan Tang, Yan Zou, Dian-Ying Liao, Yan-mei Liu and Sha Zhao
    Citation: Diagnostic Pathology 2013 8:43
    Content type: Case Report Published on:

  43. Parapharyngeal liposarcoma is a very rare malignant tumor that often causes nonspecific clinical symptoms, such as progressive dysphagia, globus sensation and/or respiratory disturbances. The combination of ra...

    Authors: Hong Li, Xueqin Zhou, Qian Ran and Liuqian Wang
    Citation: Diagnostic Pathology 2013 8:42
    Content type: Debate Published on:

  45. As a proinflammatory cytokine, interleukin-17 (IL-17) contributes to the inflammation of many autoimmune diseases. We examined IL-17 levels in serum and tissues from patients with chronic hepatitis B virus inf...

    Authors: Wen-Jun Du, Jun-Hui Zhen, Zhao-Qing Zeng, Zhao-Min Zheng, Yan Xu, Lai-Ying Qin and Shi-Jun Chen
    Citation: Diagnostic Pathology 2013 8:40
    Content type: Research Published on:

  47. Gastric cancer is a leading causes of cancer-related deaths ,but the underlying molecular mechanisms of its progression are largely unknown. Differentiated embryonic chondrocyte-expressed gene 1 (DEC1), is an ...

    Authors: Yan-Fei Jia, Dong-Jie Xiao, Xiao-Li Ma, Yan-Yan Song, Rui Hu, Yi Kong, Yan Zheng, Shu-Yi Han, Ruan-Li Hong and Yun-Shan Wang
    Citation: Diagnostic Pathology 2013 8:37
    Content type: Research Published on:

  48. Primary leiomyosarcomas of the thyroid gland are extremely rare. we report a case of a 72 year-old women with a painful growing mass of the left neck with skin fistula. The patient underwent a lobectomy. The t...

    Authors: Bennani Amal, Hinde El Fatemi, Ihsane Souaf, Kaouthar Moumna and Amarti Affaf
    Citation: Diagnostic Pathology 2013 8:36
    Content type: Case Report Published on:

  50. Automated image analysis methods are becoming more and more important to extract and quantify image features in microscopy-based biomedical studies and several commercial or open-source tools are available. Ho...

    Authors: Stephan Wienert, Daniel Heim, Manato Kotani, Björn Lindequist, Albrecht Stenzinger, Masaru Ishii, Peter Hufnagl, Michael Beil, Manfred Dietel, Carsten Denkert and Frederick Klauschen
    Citation: Diagnostic Pathology 2013 8:34
    Content type: Software Published on:
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