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COVID-19 and impact on peer review

As a result of the significant disruption that is being caused by the COVID-19 pandemic we are very aware that many researchers will have difficulty in meeting the timelines associated with our peer review process during normal times.  Please do let us know if you need additional time. Our systems will continue to remind you of the original timelines but we intend to be highly flexible at this time.

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  1. Rhabdoid colorectal tumor (RCT) is a rare, highly aggressive neoplasm recurrent in elderly patients, commonly at the caecum. The molecular mechanisms underlying RCT pathogenesis remain poorly elucidated. The d...

    Authors: Massimo Pancione, Andrea Remo, Lina Sabatino, Caterina Zanella, Carolina Votino, Alessandra Fucci, Arturo Di Blasi, Giovanni Lepore, Bruno Daniele, Francesca Fenizia, Enrico Molinari, Nicola Normanno, Erminia Manfrin, Roberto Vendraminelli and Vittorio Colantuoni
    Citation: Diagnostic Pathology 2013 8:31
    Content type: Short report Published on:

  2. Gastric plasmacytoma (GP) is a rare variant of gastric lymphomas. In the exceptional event that a patient presents with GP, the lesion occupies the mucosal layer in the vast majority of cases. Here we report a...

    Authors: Maki Kanzawa, Chihoko Hirai, Yukiko Morinaga, Fumi Kawakami, Shigeo Hara, Hiroshi Matsuoka and Tomoo Itoh
    Citation: Diagnostic Pathology 2013 8:30
    Content type: Case Report Published on:

  3. Salivary Glands Malignant Neoplasms (SGMNs) account for 3-6% of head and neck cancers and 0.3% of all cancers. Tumor cells that express CD44 and CD24 exhibit a stem-cell-like behavior. CD44 is the binding site...

    Authors: Danilo Figueiredo Soave, João Paulo Oliveira da Costa, Giorgia Gobbi da Silveira, Renata Carolina Fraga Ianez, Lucinei Roberto de Oliveira, Silvia Vanessa Lourenço and Alfredo Ribeiro-Silva
    Citation: Diagnostic Pathology 2013 8:29
    Content type: Research Published on:

  4. Low-grade cribriform cystadenocarcinoma (LGCCC) is a recently described rare tumor of salivary gland which exhibits clinically indolent behavior. This tumor predominantly consists of intraductal components and...

    Authors: Liang Wang, Yang Liu, Xuyong Lin, Di Zhang, Qingchang Li, Xueshan Qiu and En-Hua Wang
    Citation: Diagnostic Pathology 2013 8:28
    Content type: Case Report Published on:

  5. The recent development of antibodies specific for the major hotspot mutations in the epidermal growth factor receptor (EGFR), L858R and E746_A750del, may provide an opportunity to use immunohistochemistry (IHC...

    Authors: Yan Xiong, Yun Bai, Nufatt Leong, Todd S Laughlin, Paul G Rothberg, Haodong Xu, Lin Nong, Jing Zhao, Ying Dong and Ting Li
    Citation: Diagnostic Pathology 2013 8:27
    Content type: Research Published on:

  6. Tumor-to-tumor metastasis is a fairly rare phenomenon. The lung cancers are the most common donors, but are exceedingly rare as recipients. Here we report a case of a lung adenocarcinoma acting as the recipien...

    Authors: Liyan Xue, Zhonghua Luan, Ying Liu, Shuangmei Zou, Jun Jiang, Ning Wu, Ning Lu and Dongmei Lin
    Citation: Diagnostic Pathology 2013 8:26
    Content type: Case Report Published on:

  7. The uterine endometrial polyp (EMP) has a potential risk of developing malignant tumors especially in postmenopausal women. These malignancies include endometrial intraepithelial carcinoma (EIC).

    Authors: Masanori Yasuda, Tomomi Katoh, Shinichi Hori, Kimiyoshi Suzuki, Kisaku Ohno, Masanori Maruyama, Naruaki Matsui, Sayuri Miyazaki, Naoki Ogane and Yoichi Kameda
    Citation: Diagnostic Pathology 2013 8:25
    Content type: Case Report Published on:

  8. Bacterial sepsis induced immunsuppression via antigen hyporesponsibility increases the risk of nosokomial infections and mortality. Pattern recognition receptors (PRR) might have a central role in the pathophy...

    Authors: Tobias van Bremen, Daniel Drömann, Karin Luitjens, Christoph Dodt, Klaus Dalhoff, Torsten Goldmann and Bernhard Schaaf
    Citation: Diagnostic Pathology 2013 8:24
    Content type: Research Published on:

  9. Sertoliform cystadenoma of the rete testis represents an uncommon benign tumour. They appear in patients from 26 to 62 years of age. We describe a case of a 66-year-old man with a tumour in the area of the epi...

    Authors: Felix Bremmer, Stefan Schweyer, Carl Ludwig Behnes, Manfred Blech and Heinz Joachim Radzun
    Citation: Diagnostic Pathology 2013 8:23
    Content type: Case Report Published on:

  10. Virtual microscopy includes digitisation of histology slides and the use of computer technologies for complex investigation of diseases such as cancer. However, automated image analysis, or website publishing ...

    Authors: Matloob Khushi, Georgina Edwards, Diego Alonso de Marcos, Jane E Carpenter, J Dinny Graham and Christine L Clarke
    Citation: Diagnostic Pathology 2013 8:22
    Content type: Software Published on:

  11. We investigated the immunohistochemical expression of p53, MAPK, topoisomerase II alpha (topoII alpha) and Ki67 in ovarian serous carcinomas (OSCs) along with mutational analysis for KRAS and BRAF.

    Authors: Dinka Sundov, Ana Caric, Ivana Mrklic, Dijana Gugic, Vesna Capkun, Irena Drmic Hofman, Branka Petric Mise and Snjezana Tomic
    Citation: Diagnostic Pathology 2013 8:21
    Content type: Research Published on:

  13. Neuroendocrine carcinoma of the urinary bladder is a rare entity, accounting less then 1% of urinary bladder malignancies. The vast majority of the neuroendocrine carcinoma of the urinary bladder is represente...

    Authors: Cristina Colarossi, Piero Pino, Dario Giuffrida, Eleonora Aiello, Rosario Costanzo, Daniela Martinetti and Lorenzo Memeo
    Citation: Diagnostic Pathology 2013 8:19
    Content type: Case Report Published on:

  14. Sclerosing rhabdomyosarcoma (SRMS) is exceedingly rare, and may cause a great diagnostic confusion. Histologically, it is characterized by abundant extracellular hyalinized matrix mimicking primitive chondroid...

    Authors: Xu-Yong Lin, Yan Wang, Juan-Han Yu, Yang Liu, Liang Wang, Qing-Chang Li and En-Hua Wang
    Citation: Diagnostic Pathology 2013 8:18
    Content type: Case Report Published on:

  15. Amplification of the human epidermal growth factor receptor 2 (HER2) is a prognostic marker for poor clinical outcome and a predictive marker for therapeutic response to targeted therapies in breast cancer pat...

    Authors: Daniela Furrer, Simon Jacob, Chantal Caron, François Sanschagrin, Louise Provencher and Caroline Diorio
    Citation: Diagnostic Pathology 2013 8:17
    Content type: Research Published on:

  17. Eccrine carcinoma is an extremely rare malignancy of the skin with few well documented cases reported in the literature. It is frequently found on the lower extremities, and it equally affects both sexes in th...

    Authors: Karima Idrissi Serhrouchni, Taoufiq Harmouch, Laila Chbani, Hind El Fatemi, Mohammed Sekal, Nawal Hammas, Meriem Soughi, Loubna Benchat and Afaf Amarti
    Citation: Diagnostic Pathology 2013 8:15
    Content type: Case Report Published on:

  18. Mammary sarcoma is extremely rare and the diagnosis is established only after metaplastic carcinomas and malignant phyllodes tumours are excluded. A rare case of not otherwise specified-type sarcoma with CD10 ...

    Authors: Guang-Zhi Yang, Jing Li, Hua Jin and Hua-Ye Ding
    Citation: Diagnostic Pathology 2013 8:14
    Content type: Case Report Published on:

  19. The infiltration of mononuclear cells and replication and migration of smooth muscle cells (SMCs) from media into the intima in the vascular wall are the cardinal pathological changes in the early stage of chr...

    Authors: Dongfeng Gu, Yanling Shi, Yanan Ding, Xinyu Liu and Hequn Zou
    Citation: Diagnostic Pathology 2013 8:13
    Content type: Research Published on:

  21. Human epididymis protein 4 (HE4) is a novel and specific biomarker for ovarian cancer. The aim of this study is to evaluate a new tumor marker, HE4, in comparison with CA125 in diagnosis of epithelial ovarian ...

    Authors: Elham O Hamed, Hydi Ahmed, Osama B Sedeek, Abeer M Mohammed, Ali A Abd-Alla and Hazem M Abdel Ghaffar
    Citation: Diagnostic Pathology 2013 8:11
    Content type: Research Published on:

  22. Despite their pivotal roles in colorectal carcinogenesis, the interrelationship and prognostic significance of beta-catenin alterations and microsatellite instability (MSI) in colorectal cancer (CRC) needs to ...

    Authors: Sakarias Wangefjord, Jenny Brändstedt, Kajsa Ericson Lindquist, Björn Nodin, Karin Jirström and Jakob Eberhard
    Citation: Diagnostic Pathology 2013 8:10
    Content type: Research Published on:

  23. Tissue microarray (TMA) is a high throughput research tool, which has greatly facilitated and accelerated in situ tissue analyses. However, its productivity has been restricted due to the confined thickness of tr...

    Authors: Yuan Shi, Deming He, Yingyong Hou, Qin Hu, Chen Xu, Yalan Liu, Dongxian Jiang, Jieakesu Su, Haiying Zeng and Yunshan Tan
    Citation: Diagnostic Pathology 2013 8:9
    Content type: Methodology Published on:

  24. To evaluate the expression levels of Cyclin D1 in breast papillomas and papillary carcinomas, and to analyze the types of cells that co-express Cyclin D1 with Cytokeratin 5/6 (CK 5/6) or with Cytokeratin 8/18(...

    Authors: Yu Wang, Jin-fu Zhu, Ying-ying Liu and Gui-ping Han
    Citation: Diagnostic Pathology 2013 8:8
    Content type: Research Published on:

  25. Epigenetic silencing of tumor suppressor genes plays important role in gliomagenesis. Recently, GATA4 and DcR1 were suggested to be a tumor suppressor genes involved in tumorigenesis in various types of human can...

    Authors: Paulina Vaitkienė, Daina Skiriutė, Kęstutis Skauminas and Arimantas Tamašauskas
    Citation: Diagnostic Pathology 2013 8:7
    Content type: Research Published on:

  26. This study is an analysis of the prevalence of polymorphous low grade adenocarcinoma (PLGA) in epidemiological surveys of salivary tumors published in the English language from 1992 to 2012.

    Authors: Vera Cavalcanti de Araujo, Fabricio Passador-Santos, Cecilia Turssi, Andresa Borges Soares and Ney Soares de Araujo
    Citation: Diagnostic Pathology 2013 8:6
    Content type: Research Published on:

  27. Amplification of MYCN oncogene is an established marker indicating aggressive tumor progression of neuroblastoma (NBL). But copy number analyses of MYCN gene in ganglioneuroblastoma (GNBL) and ganglioneuroma(GN) ...

    Authors: Miao Wang, Chunju Zhou, Rongqin Cai, Yong Li and Liping Gong
    Citation: Diagnostic Pathology 2013 8:5
    Content type: Research Published on:

  28. Metastatic renal cell carcinoma in the gallbladder is extremely rare, with reported frequencies of less than 0.6% in large autopsy reviews. Only 40 cases were reported in the literature. We report a first case...

    Authors: Merieme Ghaouti, Kaoutar Znati, Ahmed Jahid, Fouad Zouaidia, Zakiya Bernoussi, Youssef El Fakir and Najat Mahassini
    Citation: Diagnostic Pathology 2013 8:4
    Content type: Case Report Published on:

  30. A 7-year-old boy with no history of malnutrition or diarrhoea complained of acute abdominal pain, was diagnosed with acute appendicitis, and underwent appendectomy. Histologically, a diffuse infiltrate of larg...

    Authors: Yoshifumi Matsushita and Morishige Takeshita
    Citation: Diagnostic Pathology 2013 8:2
    Content type: Case Report Published on:

  31. MicroRNA-372 (miR-372) acts as either an oncogenic miRNA or an anti-oncomiR in various human malignancies. However, its roles in gliomas have not been elucidated. To address this problem, we here detected miR-...

    Authors: Gang Li, Zhiguo Zhang, Yanyang Tu, Tianbo Jin, Hongjuan Liang, Guangbin Cui, Shiming He and Guodong Gao
    Citation: Diagnostic Pathology 2013 8:1
    Content type: Research Published on:

  32. Perivascular epithelioid cell neoplasms (PEComas) of the urinary bladder are extremely rare and the published cases were comprised predominantly of middle-aged patients. Herein, the authors present the first u...

    Authors: Lijuan Yin, Hong Bu, Min Chen, Jianqun Yu, Hua Zhuang, Jie Chen and Hongying Zhang
    Citation: Diagnostic Pathology 2012 7:183
    Content type: Case Report Published on:

  33. Little is known about the relationship between splenic arteriolar hyaline and cause of death. The purpose of this retrospective study was to evaluate the clinicopathological significance of splenic arteriolar ...

    Authors: Hirokazu Kotani, Masashi Miyao, Sho Manabe, Tokiko Ishida, Chihiro Kawai, Hitoshi Abiru and Keiji Tamaki
    Citation: Diagnostic Pathology 2012 7:182
    Content type: Research Published on:

  35. ATP-binding cassette sub-family G member 2 (ABCG2) is a protein that in humans is encoded by the ABCG2 gene. ABCG2 participates in efflux of many chemotherapeutic agents. ABCG2 is often expressed in hematopoie...

    Authors: Lijun Huang, Qiang Lu, Yong Han, Zhe Li, Zhipei Zhang and Xiaofei Li
    Citation: Diagnostic Pathology 2012 7:180
    Content type: Research Published on:

  36. Squamous cell carcinoma is the major pathology type of esophageal cancer in China, where adenocarcinoma is rare and adenoid cystic carcinoma (ACC) is more rare comparing to the western countries. We report the...

    Authors: Xu-feng Guo, Ten Mao, Zhi-tao Gu, Wen-tao Fang, Wen-hu Chen and Jin-chen Shao
    Citation: Diagnostic Pathology 2012 7:179
    Content type: Case Report Published on:

  37. Latent membrane protein (LMP) 1 and LMP2A encoded by Epstein-Barr virus (EBV) are associated with the development of malignancies, but their expression in extranodal NK/T-cell lymphoma, nasal type (ENKTL) and ...

    Authors: Yuan Mao, Da-Wei Zhang, Huijun Zhu, Hong Lin, Lin Xiong, Qing Cao, Ying Liu, Qing-Dong Li, Jia-Ren Xu, Lin-Feng Xu and Ren-Jie Chen
    Citation: Diagnostic Pathology 2012 7:178
    Content type: Research Published on:

  38. An online consultation system using virtual slides (whole slide images; WSI) has been developed for pathological diagnosis, and could help compensate for the shortage of pathologists, especially in the field o...

    Authors: Ikunori Nakayama, Tsubasa Matsumura, Akihisa Kamataki, Miwa Uzuki, Kenji Saito, James Hobbs, Toshihide Akasaka and Takashi Sawai
    Citation: Diagnostic Pathology 2012 7:177
    Content type: Research Published on:

  39. Ultrasound-guided percutaneous renal biopsy is an important technique for diagnosis of glomerular diseases, and the biopsy-induced life-threatening bleeding rarely happens. Primary systemic amyloidosis is a ra...

    Authors: Qing Zhang, Yongqiang Ji, Tianwei He and Jianping Wang
    Citation: Diagnostic Pathology 2012 7:176
    Content type: Case Report Published on:

  40. A history of an increase in pulmonary mass was presented in the right upper lobe of a 72-year-old male. The bronchial brushing cytology specimens contained many sheet-like or three-dimensional clusters of mali...

    Authors: Sohsuke Yamada, Hirotsugu Noguchi, Atsunori Nabeshima, Takashi Tasaki, Shohei Kitada, Tetsuro Baba, Hidetaka Uramoto, Takeshi Hanagiri and Yasuyuki Sasaguri
    Citation: Diagnostic Pathology 2012 7:175
    Content type: Case Report Published on:

  41. Pulmonary sclerosing hemangioma (PSH) is an uncommon pulmonary tumor. Histologically, PSH typically consists of two types of cells, surface cuboidal cells and polygonal cells, four architectural patterns inclu...

    Authors: Xu-Yong Lin, Yan Wang, Chui-Feng Fan, Yang Liu, Juan-Han Yu, Shun-Dong Dai, Liang Wang and En-Hua Wang
    Citation: Diagnostic Pathology 2012 7:174
    Content type: Case Report Published on:

  42. Prostatic stromal sarcoma is a fairly rare tumor that constitutes approximately 0.1–0.2% of all prostatic cancers. Detailed characteristics of the tumor are still unclear due to its rarity.

    Authors: Hitoshi Yamazaki, Teppei Ohyama, Toshiki Tsuboi, Yoshinori Taoka, Dai Kohguchi, Hiroyoshi Iguchi and Teruaki Ao
    Citation: Diagnostic Pathology 2012 7:173
    Content type: Case Report Published on:

  43. Enteropathy-associated T-cell lymphoma (EATL) is a rare peripheral T-cell lymphoma which was classified into 2 types based on histology. EATL is often, but not always, associated with celiac disease. EATL type...

    Authors: Liang Wang, Yang Liu, Xu-Yong Lin, Juan-Han Yu, Yuan Miao, Xue-shan Qiu and En-Hua Wang
    Citation: Diagnostic Pathology 2012 7:172
    Content type: Case Report Published on:

  44. The association between MHTFR Ala222Val polymorphism and breast cancer (BC) risk are inconclusive. To derive a more precise estimation of the relationship, a systematic review and meta-analysis was performed.

    Authors: Liwa Yu and Jianqiu Chen
    Citation: Diagnostic Pathology 2012 7:171
    Content type: Research Published on:

  45. Breast cancer may be classified into luminal A, luminal B, HER2+/ER-, basal-like and normal-like subtypes based on gene expression profiling or immunohistochemical (IHC) characteristics. The aim of our study i...

    Authors: Hinde El Fatemi, Sanae Chahbouni, Sofia Jayi, Kaoutar Moumna, My Abdelilah Melhouf, Abdelaziz Bannani, Omar Mesbahi and Afaf Amarti
    Citation: Diagnostic Pathology 2012 7:170
    Content type: Short report Published on:

    The Retraction Note to this article has been published in Diagnostic Pathology 2013 8:127

  46. This case report describes a sudden cardiac death in an apparent healthy 11-month-old infant caused by a multifocal cardiac rhabdomyoma. Parents reported that a few days before the child had fallen to the grou...

    Authors: Margherita Neri, Sabina Di Donato, Rocco Maglietta, Cristoforo Pomara, Irene Riezzo, Emanuela Turillazzi and Vittorio Fineschi
    Citation: Diagnostic Pathology 2012 7:169
    Content type: Case Report Published on:

  47. Iron deficiency anemia (IDA) is a major health problem during pregnancy and it has adverse effects on the mother and the newborn. Red cell distribution width (RDW), which is a quantitative measure for red cell...

    Authors: Esam G Abdelrahman, Gasim I Gasim, Imad R Musa, Leana M Elbashir and Ishag Adam
    Citation: Diagnostic Pathology 2012 7:168
    Content type: Research Published on:

  48. The differential diagnosis between idiopathic nonspecific interstitial pneumonia(INSIP) and idiopathic pulmonary fibrosis(IPF)/usual interstitial pneumonia(UIP)is tough in both clinicians and pathologists. In ...

    Authors: Xia Fang, Benfang Luo, Xianghua Yi, Yu Zeng, Fang Liu, Huiping Li, Pan Gu, Xuyou Zhu, Suxia Zhang and Gelin Jiang
    Citation: Diagnostic Pathology 2012 7:167
    Content type: Case Report Published on:

  49. Dermatofibrosarcoma protuberans is a locally aggressive mesenchymal neoplasm. It usually presents as an indurated plaque that protrudes above the surface of the skin. Some patients have clinically persistent p...

    Authors: Jianjun Qiao, Kayuri U Patel, Dolores López-Terrada and Hong Fang
    Citation: Diagnostic Pathology 2012 7:166
    Content type: Case Report Published on:

  50. Lung cancer most often presents as an inoperable tumour and the diagnosis is usually performed on a small biopsy/cytology specimen. In the group of non small cell lung cancer - not otherwise specified, adenoca...

    Authors: Renata Beljan Perak, Merica Glavina Durdov, Vesna Capkun, Veljka Ivcevic, Antonia Pavlovic, Violeta Soljic and Mari Peric
    Citation: Diagnostic Pathology 2012 7:165
    Content type: Research Published on:
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Diagnostic Pathology

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