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  1. Content type: Research

    Colorectal cancer is the major cause of cancer mortality, despite development of therapeutic strategies. The novel marker tumor necrosis factor receptor-associated protein 1 (TRAP1) is a mitochondrial heat sho...

    Authors: Min Gyoung Pak, Hyong Jong Koh and Mee Sook Roh

    Citation: Diagnostic Pathology 2017 12:6

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  2. Content type: Research

    Despite new treatment options for hepatocellular carcinomas (HCC) recently, 5-year survival remains poor, ranging from 50 to 70%, which may attribute to the lack of early diagnostic biomarkers. Thus, developin...

    Authors: Feifei Wang, Ruliang Wang, Qiuwen Li, Xueling Qu, Yixin Hao, Jingwen Yang, Huixia Zhao, Qian Wang, Guanghui Li, Fengyun Zhang, He Zhang, Xuan Zhou, Xioumei Peng, Yang Bian and Wenhua Xiao

    Citation: Diagnostic Pathology 2017 12:4

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  3. Content type: Research

    Double-hit lymphomas (DHL) are rare high-grade neoplasms characterized by two translocations: one involving the gene MYC and another involving genes BCL2 or BCL6, whose diagnosis depends on cytogenetic examinatio...

    Authors: Cristiano Claudino Oliveira, Helena Maciel-Guerra, Luan Kucko, Eric Jun Hirama, Américo Delgado Brilhante, Francisco Carlos Quevedo, Isabela Werneck da Cunha, Fernando Augusto Soares, Ligia Niero-Melo, Patrícia Pintor dos Reis and Maria Aparecida Custodio Domingues

    Citation: Diagnostic Pathology 2017 12:3

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  4. Content type: Research

    The Cks1 protein is an essential factor in regulating cell cycle by mediating the ubiquitination of CDK inhibitor p27kip1. It has been reported that aberrant expression of Cks1 and p27kip1 proteins was found in v...

    Authors: Lina Xu, Songqing Fan, Jin Zhao, Peng Zhou, Shuzhou Chu, Jiadi Luo, Qiuyuan Wen, Lingjiao Chen, Sailan Wen, Li Wang and Lei Shi

    Citation: Diagnostic Pathology 2017 12:2

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  5. Content type: Case Report

    Haploinsufficiency of the GATA6 transcription factor gene was recently found to be the most common cause of pancreatic agenesis, a rare cause of neonatal diabetes mellitus. Although most cases are de novo, we des...

    Authors: Daphne Yau, Elisa De Franco, Sarah E. Flanagan, Sian Ellard, Miriam Blumenkrantz and John J. Mitchell

    Citation: Diagnostic Pathology 2017 12:1

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  6. Content type: Case Report

    Diffuse large B-cell lymphoma (DLBCL) typically leads to effacement of the nodal architecture by an infiltrate of malignant cells. Rarely (<1%), DLBCL can present with an interfollicular pattern (DLBCL-IF) pre...

    Authors: Joseph Hatem, April M. Schrank-Hacker, Christopher D. Watt, Jennifer J. D. Morrissette, Adam I. Rubin, Ellen J. Kim, Sunita D. Nasta, Mariusz A. Wasik and Agata M. Bogusz

    Citation: Diagnostic Pathology 2016 11:137

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  7. Content type: Research

    The origin and heterogeneity of hepatic progenitor cells (HPCs) remain unclear. This study aimed to investigate the involvement of epithelial-mesenchymal transition (EMT) in the histogenesis of HPCs.

    Authors: Wei Xu, Nong-Rong Wang, Hua-Feng Wang, Qiong Feng, Jun Deng, Zhi-Qiang Gong, Jian Sun, Xiao-Liang Lou, Xue-Feng Yu, Lv Zhou, Jin-Ping Hu, Xiao-Feng Huang, Xiao-Qing Qi, Yan-Juan Deng, Rui Gong, Yan Guo…

    Citation: Diagnostic Pathology 2016 11:136

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  8. Content type: Research

    Acute exacerbation of idiopathic pulmonary fibrosis (AE-IPF) has high short-term mortality with unknown causes. To predict this malignant condition in clinics is challenging. In this study, we aim to demonstra...

    Authors: Haiyan Min, Shanshan Fan, Shiyu Song, Yi Zhuang, Hui Li, Yongzheng Wu, Hourong Cai, Long Yi, Jinghong Dai and Qian Gao

    Citation: Diagnostic Pathology 2016 11:135

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  9. Content type: Case Report

    Calcifying epithelial odontogenic tumor (CEOT) is a rare benign neoplasia, locally aggressive, that tends to invade bone and adjacent soft tissues. This case report describes the thirteenth known case of CEOT ...

    Authors: Cristina Munteanu, Daniel Pirici, Alex Emilian Stepan, Adrian Camen and Claudiu Margaritescu

    Citation: Diagnostic Pathology 2016 11:134

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  10. Content type: Case Report

    Inhibition of the oncogenic fusion-gene EML4-ALK is a current first-line approach for patients with stage IV non-small cell lung cancer. While FISH was established as the gold standard for identifying these pa...

    Authors: Anna-Lena Volckmar, Volker Endris, Farastuk Bozorgmehr, Clemens Lier, Carlota Porcel, Martina Kirchner, Jonas Leichsenring, Roland Penzel, Michael Thomas, Peter Schirmacher, Arne Warth and Albrecht Stenzinger

    Citation: Diagnostic Pathology 2016 11:133

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  11. Content type: Research

    Signet ring cells (SRCs) often accompany gastrointestinal carcinoma, referred to as SRC carcinoma; however, breast cancers containing SRCs have not been well characterized, leaving the prognostic significance ...

    Authors: Ryuji Ohashi, Ayako Hayama, Keiko Yanagihara, Koji Yamashita, Takashi Sakatani, Hiroyuki Takei and Zenya Naito

    Citation: Diagnostic Pathology 2016 11:131

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  12. Content type: Case Report

    Inflammatory myofibroblastic tumor (IMT) is a rare low-grade malignant neoplasm with a predilection for children and young adults, and typically arises in the lung, abdominopelvic region, and retroperitoneum. ...

    Authors: Yoko Tateishi, Koji Okudela, Shigeo Kawai, Takehisa Suzuki, Shigeaki Umeda, Mai Matsumura, Mitomu Kioi and Kenichi Ohashi

    Citation: Diagnostic Pathology 2016 11:132

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  13. Content type: Case Report

    Uterine serous endometrial intraepithelial carcinoma (SEIC) is an immediate precursor of invasive carcinoma. The majority of stage IA SEICs are curable, but those with latent peritoneal metastasis and/or capil...

    Authors: Mitsuko Furuya, Teiko Sato, Reiko Tanaka, Masafumi Yamamoto, Naho Ruiz Yokota and Etsuko Miyagi

    Citation: Diagnostic Pathology 2016 11:130

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  14. Content type: Research

    As the World Health Organization grading system for gastroenteropancreatic-neuroendocrine tumors (GEP-NETs) may not always correlate with tumor progression, it is imperative that other independent predictors o...

    Authors: Yoichiro Okubo, Osamu Motohashi, Norisuke Nakayama, Ken Nishimura, Rika Kasajima, Yohei Miyagi, Manabu Shiozawa, Emi Yoshioka, Masaki Suzuki, Kota Washimi, Kae Kawachi, Madoka Nito, Yoichi Kameda and Tomoyuki Yokose

    Citation: Diagnostic Pathology 2016 11:128

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  15. Content type: Retraction Note

    Authors: Abbas Tavasoly, Javad Javanbakht, Fariba Khaki, Ehsan Hosseini, Alimohammad Bahrami, Mehdi Aghamohammad Hassan and Mohammadmehdi Mirabad

    Citation: Diagnostic Pathology 2016 11:121

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    The original article was published in Diagnostic Pathology 2013 8:777

  16. Content type: Retraction Note

    Authors: Omid Maghsoudi, Seyed Hesamoddin Mirjalili, Mojtaba Dolatabadi, Mostafa Fallah Joshaghani, Mojtaba Zarea, Emad Yahaghi and Aram Mokarizadeh

    Citation: Diagnostic Pathology 2016 11:114

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    The original article was published in Diagnostic Pathology 2015 10:98

  17. Content type: Retraction Note

    Authors: Farajollah Adib-Hashemi, Farshad Farahmand, Shamim Fattah Hesari, Bijan Rezakhaniha, Ehsan Fallah, Amir Farshid Fayyaz and Masoomeh Dadpay

    Citation: Diagnostic Pathology 2016 11:118

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    The original article was published in Diagnostic Pathology 2015 10:19

  18. Content type: Retraction Note

    Authors: Afshin Taheriazam, Amir Jouya Talaei, Mohammad Jamshidi, Mohammadreza Shakeri, Samaneh Khoshbakht, Emad Yahaghi and Marjan Shokrani

    Citation: Diagnostic Pathology 2016 11:112

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    The original article was published in Diagnostic Pathology 2015 10:184

  19. Content type: Retraction Note

    Authors: Javad Yaghoobi Yeganeh Manesh, Radmehr Shafiee, Ali Mohammad Bahrami, Mehdi Pourzaer, Maryam Pourzaer, Behnam Pedram, Javad Javanbakht, Aram Mokarizadeh and Farshid Khadivar

    Citation: Diagnostic Pathology 2016 11:115

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    The original article was published in Diagnostic Pathology 2014 9:999

  20. Content type: Retraction Note

    Authors: Naeemeh Ghasemkhani, Sahar Shadvar, Yasamin Masoudi, Amir Jouya Talaei, Emad Yahaghi, Peyman Karimi Goudarzi and Ebrahim Shakiba

    Citation: Diagnostic Pathology 2016 11:110

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    The original article was published in Diagnostic Pathology 2015 10:164

  21. Content type: Retraction Note

    Authors: Radmehr Shafiee, Javad Javanbakht, Nahid Atyabi, Alimohammad Bahrami, Danial Kheradmand, Reyhaneh Safaei, Farshid Khadivar and Ehsan Hosseini

    Citation: Diagnostic Pathology 2016 11:116

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    The original article was published in Diagnostic Pathology 2013 8:136

  22. Content type: Retraction Note

    Authors: Fariba Khaki, Javad Javanbakht, Farhang Sasani, Mohammad Javad Gharagozlou, Alimohammad Bahrami, Hemmat Moslemzadeh and Reza Sheikhzadeh

    Citation: Diagnostic Pathology 2016 11:107

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    The original article was published in Diagnostic Pathology 2013 8:98

  23. Content type: Retraction Note

    Authors: Samad Alimohammadi, Rahim Hobbenaghi, Javad Javanbakht, Danial Kheradmand, Reza Mortezaee, Maryam Tavakoli, Farshid Khadivar and Hamid Akbari

    Citation: Diagnostic Pathology 2016 11:125

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    The original article was published in Diagnostic Pathology 2013 8:137

  24. Content type: Retraction Note

    Authors: Ehsan Hosseini, Behnam Pedram, Ali Mohammad Bahrami, Mohammad Hossein Jaberi Moghaddam, Javad Javanbakht, Fatemeh Emami Ghomi, Najme Jaberi Moghaddam, Mobin Koohestani and Radmehr Shafiee

    Citation: Diagnostic Pathology 2016 11:106

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    The original article was published in Diagnostic Pathology 2014 9:9

  25. Content type: Retraction Note

    Authors: Alireza Nasoori, Behnam Pedram, Zahra Kamyabi-Moghaddam, Aram Mokarizadeh, Hamid Pirasteh, Amir Farshid Fayyaz and Mohammad Barat Shooshtari

    Citation: Diagnostic Pathology 2016 11:123

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    The original article was published in Diagnostic Pathology 2015 10:23

  26. Content type: Retraction Note

    Authors: Rahim Hobbenaghi, Javad Javanbakht, Ehan Hosseini, Shahin Mohammadi, Mojtaba Rajabian, Pedram Moayeri and Mehdi Aghamohammad Hassan

    Citation: Diagnostic Pathology 2016 11:109

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    The original article was published in Diagnostic Pathology 2013 8:123

  27. Content type: Retraction Note

    Authors: Rahim Hobbenaghi, Pariya Mahboob, Siamak Saifzadeh, Javad Javanbakht, Javad Yaghoobi Yeganeh Manesh, Rasool Mortezaee, Seyed Rashid Touni, Ehsan Hosseini, Shahin Aghajanshakeri, Milad Moloudizargari and Soheil Javaherypour

    Citation: Diagnostic Pathology 2016 11:124

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    The original article was published in Diagnostic Pathology 2014 9:59

  28. Content type: Retraction Note

    Authors: Fardin Barati, Javad Javanbakht, Farajollah Adib-Hashemi, Ehsan Hosseini, Reyhaneh Safaeie, Mojtaba Rajabian, Mostafa Razmjoo, Reza Sedaghat and Mehdi Aghamohammad Hassan

    Citation: Diagnostic Pathology 2016 11:117

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    The original article was published in Diagnostic Pathology 2013 8:826

  29. Content type: Research Article

    Metanephric adenoma (MA) is a benign renal tumor that is difficult to distinguish from a malignant tumor via traditional radiography. The diagnosis of MA is often dependent on postsurgical histopathological ex...

    Authors: Jing Yan, Jing-Liang Cheng, Chen-Fei Li, Yan-Bang Lian, Yuan Zheng, Xue-Ping Zhang and Chao-Yan Wang

    Citation: Diagnostic Pathology 2016 11:104

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  30. Content type: Research

    To assess the quality of sweat test (ST) based on the proportion of sweat sodium and sweat chloride as diagnostic parameter of cystic fibrosis (CF).

    Authors: Alethéa Guimarães Faria, Fernando Augusto Lima Marson, Carla Cristina de Souza Gomez, Maria Ângela Gonçalves de Oliveira Ribeiro, Lucas Brioschi Morais, Maria de Fátima Servidoni, Carmen Sílvia Bertuzzo, Eulália Sakano, Maura Goto, Ilma Aparecida Paschoal, Mônica Corso Pereira, Gabriel Hessel, Carlos Emílio Levy, Adyléia Aparecida Dalbo Contrera Toro, Andressa Oliveira Peixoto, Maria Cristina Ribeiro Simões…

    Citation: Diagnostic Pathology 2016 11:103

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    The Erratum to this article has been published in Diagnostic Pathology 2017 12:22

  31. Content type: Research

    HER2/neu overexpression and/or amplification has been widely studied in a number of solid tumors, primarily in the breast. In gynecologic neoplasms, determination of HER2/neu status has not been well studied as a...

    Authors: Jennifer S. Woo, Sophia K. Apple, Peggy S. Sullivan, Jian-Yu Rao, Nora Ostrzega and Neda A. Moatamed

    Citation: Diagnostic Pathology 2016 11:102

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  32. Content type: Case Report

    Mitotically active cellular fibroma (MACF) of the ovary, characterized by relatively high mitotic activity without severe atypia, represents a relatively new disease entity. MACF is categorized as a benign ova...

    Authors: Katsuya Matsuda, Seiko Tateishi, Yuko Akazawa, Akira Kinoshita, Shiko Yoshida, Sachiko Morisaki, Ai Fukushima, Takahiro Matsuwaki, Koh-Ichiro Yoshiura and Masahiro Nakashima

    Citation: Diagnostic Pathology 2016 11:101

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  33. Content type: Research

    Isolated hypothalamic-pituitary Langerhans cell histiocytosis (HPLCH) is very rare. We investigated the clinicopathological characteristics, endocrine function changes, BRAFV600E mutations and treatments of isola...

    Authors: Zhen Huo, Tao Lu, Zhiyong Liang, Fan Ping, Jie Shen, Jingjing Lu, Wenbing Ma, Dachun Zhao and Dingrong Zhong

    Citation: Diagnostic Pathology 2016 11:100

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  34. Content type: Case Report

    Rhabdomyosarcoma (RMS) is a malignant tumor of mesenchymal origin and comprises the largest category of soft-tissue sarcomas both in children and adolescents. From a pediatric oncology point of view, RMS has t...

    Authors: Petra Balogh, Rita Bánusz, Monika Csóka, Zsófia Váradi, Edit Varga and Zoltán Sápi

    Citation: Diagnostic Pathology 2016 11:99

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  35. Content type: Methodology

    The assessment of TP53 mutational status is becoming a routine clinical practice for chronic lymphocytic leukemia patients (CLL). A broad spectrum of molecular techniques has been employed so far, including both ...

    Authors: Crescenzio Francesco Minervini, Cosimo Cumbo, Paola Orsini, Claudia Brunetti, Luisa Anelli, Antonella Zagaria, Angela Minervini, Paola Casieri, Nicoletta Coccaro, Giuseppina Tota, Luciana Impera, Annamaria Giordano, Giorgina Specchia and Francesco Albano

    Citation: Diagnostic Pathology 2016 11:96

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  36. Content type: Research

    A high-quality programmed cell-death ligand 1 (PD-L1) diagnostic assay may help predict which patients are more likely to respond to anti-programmed cell death-1 (PD-1)/PD-L1 antibody-based cancer therapy. Her...

    Authors: Marlon C. Rebelatto, Anita Midha, Amita Mistry, Constantine Sabalos, Nicole Schechter, Xia Li, Xiaoping Jin, Keith E. Steele, Paul B. Robbins, John A. Blake-Haskins and Jill Walker

    Citation: Diagnostic Pathology 2016 11:95

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  37. Content type: Case Report

    Understanding the role of alternative complement pathway dysregulation in membranoproliferative glomerulonephritis (MPGN) has led to a dramatic shift in its classification into two subgroups: immune complex-me...

    Authors: Tanja Kersnik Levart, Dušan Ferluga, Alenka Vizjak, Jerica Mraz and Nika Kojc

    Citation: Diagnostic Pathology 2016 11:94

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