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  1. Iron deficiency anemia (IDA) is a major health problem during pregnancy and it has adverse effects on the mother and the newborn. Red cell distribution width (RDW), which is a quantitative measure for red cell...

    Authors: Esam G Abdelrahman, Gasim I Gasim, Imad R Musa, Leana M Elbashir and Ishag Adam
    Citation: Diagnostic Pathology 2012 7:168
    Content type: Research Published on:

  2. Dermatofibrosarcoma protuberans is a locally aggressive mesenchymal neoplasm. It usually presents as an indurated plaque that protrudes above the surface of the skin. Some patients have clinically persistent p...

    Authors: Jianjun Qiao, Kayuri U Patel, Dolores López-Terrada and Hong Fang
    Citation: Diagnostic Pathology 2012 7:166
    Content type: Case Report Published on:

  3. Lung cancer most often presents as an inoperable tumour and the diagnosis is usually performed on a small biopsy/cytology specimen. In the group of non small cell lung cancer - not otherwise specified, adenoca...

    Authors: Renata Beljan Perak, Merica Glavina Durdov, Vesna Capkun, Veljka Ivcevic, Antonia Pavlovic, Violeta Soljic and Mari Peric
    Citation: Diagnostic Pathology 2012 7:165
    Content type: Research Published on:

  4. The 4 present cases with endometrioid adenocarcinoma (EMA) of the ovary were characterized by estrogen overproduction and resemblance to sex cord-stromal tumor (SCST). The patients were all postmenopausal, at ...

    Authors: Tomomi Katoh, Masanori Yasuda, Kosei Hasegawa, Eito Kozawa, Jun-ichi Maniwa and Hironobu Sasano
    Citation: Diagnostic Pathology 2012 7:164
    Content type: Case Report Published on:

  5. Mixed adenoneuroendocrine carcinoma (MANEC) carcinomas rarely occur in the gallbladder. Here we reported a case of giant gallbladder unresectable mass with local liver invasion and omentum metastasis, which pr...

    Authors: Wu Song, Wenfang Chen, Sheng Zhang, Jianjun Peng and Yulong He
    Citation: Diagnostic Pathology 2012 7:163
    Content type: Case Report Published on:

  6. Nipple adenoma is a relatively rare benign breast neoplasm, and cases of the disease arising from the axillary accessory breast have very seldom been reported in the English literature. We report a case of nip...

    Authors: Yoshihiro Shioi, Shin-ichi Nakamura, Shuji Kawamura and Masako Kasami
    Citation: Diagnostic Pathology 2012 7:162
    Content type: Case Report Published on:

  7. On the past decade a plethora of investigations were directed on identification of molecules involved in breast tumorogenesis, which could represent a powerful tool for monitoring, diagnostics and treatment of...

    Authors: Olga Kostianets, Stepan Antoniuk, Valeriy Filonenko and Ramziya Kiyamova
    Citation: Diagnostic Pathology 2012 7:161
    Content type: Research Published on:

  8. Interstitial pneumonias (IP) cover a broad spectrum of diseases. Open lung biopsies reveal histological patterns and suggest possible diagnoses. Complete clinical records are necessary for final diagnoses. Esp...

    Authors: Dirk Theegarten, Heike Maria Müller, Francesco Bonella, Jeremias Wohlschlaeger and Ulrich Costabel
    Citation: Diagnostic Pathology 2012 7:160
    Content type: Research Published on:

  9. MicroRNA-100 (miR-100) has been demonstrated to be downregulated in bladder cancer tissues, and enforced expression of this miRNA may inhibit cell growth and colony formation of human bladder cancer 5637 cells...

    Authors: Sheng Wang, Sheng Xue, Yuanqing Dai, Jianfu Yang, Zhijun Chen, Xiwu Fang, Wensheng Zhou, Wei Wu and Qingwen Li
    Citation: Diagnostic Pathology 2012 7:159
    Content type: Research Published on:

  11. Hydatid disease, a parasitic infection is caused by Echinococcus granulosus. It has serious impact on health and economy especially in countries where it is endemic. It occurs frequently in liver and lung. The di...

    Authors: Nuzhat Sultana, Tariq Khan Hashim, Shahida Yahya Jan, Zahidullah khan, Tahir Malik and Walayat Shah
    Citation: Diagnostic Pathology 2012 7:157
    Content type: Case Report Published on:

  12. Lymphoid infiltration is a prognostic marker in solid tumors, such as colorectal, breast and lung carcinomas. However, lymphoid infiltration is heterogeneous and the reproducibility of quantification based on ...

    Authors: Marc-Antoine Allard, Jean Baptiste Bachet, Alain Beauchet, Catherine Julie, Robert Malafosse, Christophe Penna, Bernard Nordlinger and Jean-François Emile
    Citation: Diagnostic Pathology 2012 7:156
    Content type: Research Published on:

  13. Pleomorphic lipoma is a relatively uncommon entity, and is considered as a variant of spindle cell lipoma. Histologically, spindle cell lipoma/pleomorphic lipoma consists of varying quantity of mature fat, bla...

    Authors: Xu-Yong Lin, Yan Wang, Yang Liu, Ying Sun, Yuan Miao, Yong Zhang, Juan-Han Yu and En-Hua Wang
    Citation: Diagnostic Pathology 2012 7:155
    Content type: Case Report Published on:

  14. Primary sarcomas of the major blood vessels can be classified based on location in relationship to the wall or by histologic type. Angiosarcomas are malignant neoplasms that arise from the endothelial lining o...

    Authors: Olga L Bohn, Eric Acosta-Ponce de León, Oscar Lezama, Nina P Rios-Luna, Sergio Sánchez-Sosa and Antonio Llombart-Bosch
    Citation: Diagnostic Pathology 2012 7:154
    Content type: Case Report Published on:

  15. In the present case of postoperative lumbar spinal stenosis after non-instrumented intertransverse fusion with granules of hydroxyapatite (HA), bone union was not completed and the patient felt the recurrence ...

    Authors: Gen Inoue, Seiji Ohtori, Tomoyuki Ozawa, Toshinori Ito, Morihiro Higashi, Kazuyo Yamauchi, Sumihisa Orita, Junichi Nakamura, Tomoaki Toyone, Masashi Takaso and Kazuhisa Takahashi
    Citation: Diagnostic Pathology 2012 7:153
    Content type: Case Report Published on:

  16. A new modality is necessary to prevent recurrence of superficial bladder cancer after complete transurethral resection because of the high recurrence rate even with current prophylaxis protocols.

    Authors: Tomislav Tadin, Kristian Krpina, Sanja Štifter, Emina Babarović, Željko Fučkar and Nives Jonjić
    Citation: Diagnostic Pathology 2012 7:152
    Content type: Research Published on:

  18. Gastrointestinal stromal tumours (GISTs) are the most common primary mesenchymal neoplasia in the gastrointestinal tract, although they represent only a small fraction of total gastrointestinal malignancies in...

    Authors: Laura Macías-García, Haydee De la Hoz-Herazo, Antonio Robles-Frías, María J Pareja-Megía, Juan López-Garrido and José I López
    Citation: Diagnostic Pathology 2012 7:150
    Content type: Short report Published on:

  19. The ability to distinguish hepatocellular carcinoma (HCC) from metastatic carcinoma (MC) involving the liver and cholangiocarcinoma (CC) by immunohistochemistry has been limited by the lack of a reliable posit...

    Authors: Nehal A Radwan and Naglaa S Ahmed
    Citation: Diagnostic Pathology 2012 7:149
    Content type: Research Published on:

  20. As it is often difficult for a transplant pathologist to make a definite diagnosis of acute cellular rejection (ACR) by routine morphological analysis of liver allograft biopsy, supplementary methods and objec...

    Authors: Long Cheng, Fuzhou Tian, Lijun Tang, Shuguang Wang, Geng Chen, Guangjie Duan and Xiaochu Yan
    Citation: Diagnostic Pathology 2012 7:148
    Content type: Research Published on:

  21. Human papillomavirus (HPV) infection plays an etiological role in the development of cervical dysplasia and cancer. Amplification of human telomerase gene (hTERC) and over expression of telomerase were found t...

    Authors: Hongqian Liu, Shanling Liu, He Wang, Xiaoyan Xie, Xinlian Chen, Xuemei Zhang and Youcheng Zhang
    Citation: Diagnostic Pathology 2012 7:147
    Content type: Research Published on:

  22. Lung cancer is the leading cause of death among malignant diseases in humans worldwide. In the last decade development of new targeted drugs for the treatment of non-small cell lung cancer proved to be a promi...

    Authors: Claudia Otto, Agnes Csanadi, Paul Fisch, Martin Werner and Gian Kayser
    Citation: Diagnostic Pathology 2012 7:146
    Content type: Short report Published on:

  24. Colloid cysts are rare congenital, intracranial neoplasms, commonly located in the third ventricle. Colloid cysts are endodermal congenital malformations. The cysts commonly range in size from 1–2 cm in diamet...

    Authors: Emanuela Turillazzi, Stefania Bello, Margherita Neri, Irene Riezzo and Vittorio Fineschi
    Citation: Diagnostic Pathology 2012 7:144
    Content type: Case Report Published on:

  25. A 67-year-old Japanese female was followed up due to prolonged idiopathic thrombocytopenia with non-response to steroid therapy for 4 years, but recent progressive pancytopenia, hypo-albuminemia, and hypo-γ-gl...

    Authors: Sohsuke Yamada, Takashi Tasakil, Naoko Satoh, Atsunori Nabeshima, Shohei Kitada, Hirotsugu Noguchi, Kozue Yamada, Morishige Takeshita and Yasuyuki Sasaguri
    Citation: Diagnostic Pathology 2012 7:143
    Content type: Case Report Published on:

  26. It has been demonstrated that signals from the inhibitory receptor B and T lymphocyte attenuator (BTLA) are involved in regulating the pathogenesis of infectious diseases. However, the expression and anatomica...

    Authors: Huan Xu, Dayan Cao, Guoning Guo, Zhihua Ruan, Yuzhang Wu and Yongwen Chen
    Citation: Diagnostic Pathology 2012 7:142
    Content type: Research Published on:

  27. To investigate the expression of matrix metalloproteinase-2 (MMP-2) and tissue inhibitor of metallopropteinase-1 (TIMP-1) in the renal allografts of patients with chronic active antibody-mediated rejection (AM...

    Authors: Qiang Yan, Weiguo Sui, Baoyao Wang, Hequn Zou, Guimian Zou and Hao Luo
    Citation: Diagnostic Pathology 2012 7:141
    Content type: Research Published on:

  28. Leiomyomas are benign tumours that originate from smooth muscles. They are often seen in the uterus, but also in the renal pelvis, bladder, spermatic cord, epididymis, prostate, scrotum or the glans penis. Lei...

    Authors: Felix Bremmer, Felix J Kessel, Carl L Behnes, Lutz Trojan and Elmar Heinrich
    Citation: Diagnostic Pathology 2012 7:140
    Content type: Case Report Published on:

  30. In this study we report the prevalence of antiretroviral drug resistant HIV-1 genotypes of virus isolated from Djiboutian patients who failed first-line antiretroviral therapy (ART) and from ART naïve patients.

    Authors: Aden Elmi Abar, Asma Jlizi, Houssein Youssouf Darar, Mohamed Ali Ben Hadj Kacem and Amine Slim
    Citation: Diagnostic Pathology 2012 7:138
    Content type: Research Published on:

  31. Mucoepidermoid carcinoma is a common malignant epithelial tumor of salivary glands, but relatively rare in lung. The histological features of mucoepidermoid carcinoma of the lung are similar to its counterpart...

    Authors: Hong-Tao Xu, Xu-Yong Lin, Qing-Chang Li and En-Hua Wang
    Citation: Diagnostic Pathology 2012 7:137
    Content type: Case Report Published on:

  32. Catechol-O-methyltransferase (COMT) is one of the most important enzymes involved in estrogen metabolism and its functional genetic polymorphisms may be associated with breast cancer (BC) risk. Many epidemiologic...

    Authors: Xue Qin, Qiliu Peng, Aiping Qin, Zhiping Chen, Liwen Lin, Yan Deng, Li Xie, Juanjuan Xu, Haiwei Li, Taijie Li, Shan Li and Jinmin Zhao
    Citation: Diagnostic Pathology 2012 7:136
    Content type: Research Published on:

  34. Computer-based analysis of digitalized histological images has been gaining increasing attention, due to their extensive use in research and routine practice. The article aims to contribute towards the descrip...

    Authors: Harshita Sharma, Alexander Alekseychuk, Peter Leskovsky, Olaf Hellwich, RS Anand, Norman Zerbe and Peter Hufnagl
    Citation: Diagnostic Pathology 2012 7:134
    Content type: Research Published on:

  35. CD20-positive T-cell lymphoma is extremely rare and only two cases of CD20-positive NK/T-cell lymphoma with aggressive clinical courses have been described in the literature. We present a case of unusual NK/T-...

    Authors: Qing-ping Jiang, Shao-yan Liu, Yue-xin Yang, Xue-xian Tan, Juan Peng, Zhong-tang Xiong and Zhi Li
    Citation: Diagnostic Pathology 2012 7:133
    Content type: Case Report Published on:

  36. Pancreatic neuroendocrine tumors are a rare entity with an incidence between 2 per million to 5 per 100 000. Association with pancreatitis (acute or chronic) is rare and is considered to be determined by the t...

    Authors: Valeriu Surlin, Sandu Ramboiu, Mirela Ghilusi and Iancu Emil Plesea
    Citation: Diagnostic Pathology 2012 7:132
    Content type: Case Report Published on:

  37. World Health Organization (WHO) criteria are commonly used to diagnose plasma cell myeloma (PCM); however, these criteria are complex and require several laboratory parameters. For differentiating reactive pla...

    Authors: Shoko Nakayama, Taiji Yokote, Yuji Hirata, Kazuki Iwaki, Toshikazu Akioka, Takuji Miyoshi, Ayami Takayama, Uta Nishiwaki, Yuki Masuda, Toshiyuki Ikemoto, Hidema Tanaka, Yasuichiro Nishimura, Motomu Tsuji and Toshiaki Hanafusa
    Citation: Diagnostic Pathology 2012 7:131
    Content type: Research Published on:

  38. Multinucleated giant cell-containing tumors and pseudotumors of bone represent a heterogeneous group of benign and malignant lesions. Differential diagnosis can be challenging, particularly in instances of lim...

    Authors: Nawal Hammas, Chbani Laila, Alaoui Lamrani My Youssef, El Fatemi Hind, Taoufiq Harmouch, Tizniti Siham and Amarti Afaf
    Citation: Diagnostic Pathology 2012 7:130
    Content type: Research Published on:

  40. Langerhans cell sarcoma is a rare and aggressive high grade hematopoietic neoplasm with a dismal prognosis. It has a unique morphological and immunotypic profile with a CD1a/ langerin/S100 + phenotype. T cell ...

    Authors: Zhaodong Xu, Ruth Padmore, Carolyn Faught, Lisa Duffet and Bruce F Burns
    Citation: Diagnostic Pathology 2012 7:128
    Content type: Case Report Published on:

  42. Neuroendocrine tumors are a heterogeneous group of neoplasms that arise from neuroendocrine cells. Primary renal neuroendocrine tumors are among the most unusual of all renal neoplasms, since neuroendocrine ce...

    Authors: Qingfu Zhang, Jian Ming, Siyang Zhang and Xueshan Qiu
    Citation: Diagnostic Pathology 2012 7:126
    Content type: Case Report Published on:

  43. Primary mesenchymal chondrosarcoma of the kidney is rare, and it shows distinct undifferentiated tumor cells and well differentiated cartilagenous components. Also assident infiltrating urothelial carcinoma of...

    Authors: Hua Xu, MuMin Shao, HuiLi Sun and ShunMin Li
    Citation: Diagnostic Pathology 2012 7:125
    Content type: Case Report Published on:

  44. In many tumors including ovarian cancer, cell proliferation and apoptosis are important in pathogenesis and there are many alterations in most of the genes related to the cell cycle. This study was designed to...

    Authors: Hatice Ozer, GoncaImir Yenicesu, Sema Arici, Meral Cetin, Ersin Tuncer and Ali Cetin
    Citation: Diagnostic Pathology 2012 7:124
    Content type: Research Published on:

  45. Malignant melanoma involving the respiratory tract is nearly always metastatic in origin, and primary tumors are very rare. To our knowledge, about 30 cases have been reported in the English literature, one of...

    Authors: Li Gong, Xiao-Yan Liu, Wen-Dong Zhang, Shao-Jun Zhu, Li Yao, Xiu-Juan Han, Miao Lan, Yan-Hong Li and Wei Zhang
    Citation: Diagnostic Pathology 2012 7:123
    Content type: Case Report Published on:

  46. Angiomyolipoma (AML) is a rare mesenchymal neoplasm of the tumor, composed of a varying heterogeneous mixture of three tissue components: blood vessels, smooth muscle and adipose cells. Hepatic AML may demonst...

    Authors: Yang Liu, Jian Wang, Xu-Yong Lin, Hong-Tao Xu, Xue-shan Qiu and En-Hua Wang
    Citation: Diagnostic Pathology 2012 7:122
    Content type: Case Report Published on:

  48. To evaluate the expression and differential significance of c-Jun, p73, Casp-9 and N-ras in thymic epithelial tumors (TETs) with the aim to provide useful information for tumor biology and prospective therapy.

    Authors: Yuqing Ma, Qiaoxin Li, Wenli Cui, Na Miao, Xia Liu, Wei Zhang, Chen Zhang and Jian Wang
    Citation: Diagnostic Pathology 2012 7:120
    Content type: Research Published on:

  49. This study consisted of two parts. One part was to analyze the survival rates of adenoid cystic carcinoma (ACC) in Chinese and explain the difference between our data and the literature. The other was to analy...

    Authors: Quan Zhou, Hong Chang, Hongkai Zhang, Yiding Han and Honggang Liu
    Citation: Diagnostic Pathology 2012 7:119
    Content type: Research Published on:

  50. Epithelioid angiosarcoma of the parotid gland is rare, and may pose a great diagnostic challenge. We report a case of primary epithelioid angiosarcoma in a 64-year-old male without history of radiation. The hi...

    Authors: Xu-Yong Lin, Yang Liu, Yong Zhang, Juan-Han Yu and En-Hua Wang
    Citation: Diagnostic Pathology 2012 7:118
    Content type: Case Report Published on:
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