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COVID-19 and impact on peer review

As a result of the significant disruption that is being caused by the COVID-19 pandemic we are very aware that many researchers will have difficulty in meeting the timelines associated with our peer review process during normal times.  Please do let us know if you need additional time. Our systems will continue to remind you of the original timelines but we intend to be highly flexible at this time.

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  1. Association between DNA alterations and clinical parameters as recurrence, survival or prognosis has been found in a variety of tumors. A clear association between Medullary Thyroid Carcinoma (MTC) and RET onc...

    Authors: Beatriz González-Yebra, Raúl Peralta, Ana Lilia González, Marco Antonio Ayala-Garcia, María E Medrano Ortiz de Zarate and Mauricio Salcedo
    Citation: Diagnostic Pathology 2012 7:63
  2. A history of a recent rapid increase in long-standing swelling mass was presented in the right parotid gland of an 85-year-old male. The inadequate cytologic specimens contained few small clusters of three-dim...

    Authors: Sohsuke Yamada, Atsunori Nabeshima, Takahisa Tabata, Xin Guo, Takashi Tasaki, Ke-Yong Wang, Shohei Shimajiri and Yasuyuki Sasaguri
    Citation: Diagnostic Pathology 2012 7:61
  3. The eligibility of breast cancer patients for human epidermal growth factor receptor 2 (HER2)-directed therapies is determined by the HER2 gene amplification and/or HER2 protein overexpression status of the breas...

    Authors: Hiroaki Nitta, Brian D Kelly, Mary Padilla, Nikolaus Wick, Patrick Brunhoeber, Isaac Bai, Shalini Singh, Jim Ranger-Moore, Chris Bieniarz, Hitoshi Tsuda and Thomas M Grogan
    Citation: Diagnostic Pathology 2012 7:60
  4. Serrated polyps belong to a heterogeneous group of lesions that are generally characterized morphologically. This type of lesion is thought to be the precursor of sporadic carcinomas with microsatellite instab...

    Authors: Yukari Fujimori, Takahiro Fujimori, Johji Imura, Tamotsu Sugai, Takashi Yao, Ryo Wada, Yoichi Ajioka and Yasuo Ohkura
    Citation: Diagnostic Pathology 2012 7:59
  5. Renal cell carcinoma (RCC) is characterized by its resistance to radiotherapy and/or chemotherapy. On the other hand, it is an immunogenic tumor - it is able to stimulate antitumor responses. A prognostic sign...

    Authors: Leos Kren, Ivo Valkovsky, Jan Dolezel, Ivo Capak, Dalibor Pacik, Alexandr Poprach, Radek Lakomy, Martina Redova, Pavel Fabian, Zdenka Krenova and Ondrej Slaby
    Citation: Diagnostic Pathology 2012 7:58
  6. c-MET is an oncogene protein that plays important role in gastric carcinogenesis and has been introduced as a prognostic marker and potential therapeutic target. The aim of this study was to evaluate the frequ...

    Authors: Kambiz Sotoudeh, Forough Hashemi, Zahra Madjd, Alireza Sadeghipour, Saadat Molanaei and Elham Kalantary
    Citation: Diagnostic Pathology 2012 7:57
  7. To evaluate the influence of corneal astigmatism (CA) on retinal nerve fiber layer (RNFL) thickness and optic nerve head(ONH) parameters measured with spectral-domain optical coherence tomography (OCT) in high...

    Authors: Lin Liu, Jun Zou, Hui Huang, Jian-guo Yang and Shao-rong Chen
    Citation: Diagnostic Pathology 2012 7:55
  8. We previously investigated the current status of breast cytology cancer screening at seven institutes in our area of southern Fukuoka Prefecture, and found some differences in diagnostic accuracy among the ins...

    Authors: Rin Yamaguchi, Shin-ichi Tsuchiya, Takashi Koshikawa, Toshiro Yokoyama, Kuniko Mibuchi, Yasuhide Nonaka, Sonoe Ito, Hidejiro Higuchi, Mariko Nagao, Koichi Higaki, Jiro Watanabe, Masayoshi Kage and Hirohisa Yano
    Citation: Diagnostic Pathology 2012 7:53
  9. We report a 32-year-old Outer Mongolian man, with plasmablastic lymphoma (PBL) primarily occured in the central nervous system and diagnosed by surgical resection. This patient appeared headache and Magnetic r...

    Authors: Li Ying Zhang, Hui Yun Lin, Lan Xiang Gao, Lin Li, Yu Wang Tian, Zhi Qin Liu, Xiao Hua Shi and Zhi Yong Liang
    Citation: Diagnostic Pathology 2012 7:51
  10. Angioimmunoblastic T-cell lymphoma is one of the most common subtypes of peripheral T-cell lymphoma (15-20% of all cases), accounting for approximately 1-2% of all non-Hodgkin lymphomas. It often presents auto...

    Authors: Maria Raffaella Ambrosio, Bruno Jim Rocca, Alessandro Ginori, Monica Onorati, Alberto Fabbri, Mario Carmellini, Stefano Lazzi and Sergio Tripodi
    Citation: Diagnostic Pathology 2012 7:50
  11. Hemangioblastoma is a benign and morphologically distinctive tumor that can occur sporadically or in association with von Hippel-Lindau disease in approximately 25% of the cases, and which involves the central...

    Authors: Yang Liu, Xue-shan Qiu and En-Hua Wang
    Citation: Diagnostic Pathology 2012 7:49
  12. Genital rhabdomyoma is very rare tumor that usually occurs in the vulvar of young women. Epididymis rhabdomyoma in a young man is extremely uncommon and has rarely been reported. Here, we report a case of epid...

    Authors: Yang Han, Xue-shan Qiu, Qing-chang Li, Yu-chen Han, Xu-yong Lin, Qing-fu Zhang, Jian Wang, En-hua Wang and Ze-liang Li
    Citation: Diagnostic Pathology 2012 7:47
  13. Glomerular crescents are most commonly associated with rapidly progressive crescentic glomerulonephritis; however, they also develop in response to a wide range of primary and secondary glomerular injuries. Si...

    Authors: Naoko Otani, Tetsu Akimoto, Wako Yumura, Daisuke Matsubara, Yoshitaka Iwazu, Akihiko Numata, Takuya Miki, Fumi Takemoto, Noriyoshi Fukushima, Shigeaki Muto and Eiji Kusano
    Citation: Diagnostic Pathology 2012 7:46
  14. Breast cancer is one of the most common cancers in the world, and the identification of biomarkers for the early detection of breast cancer is a relevant target. The present study aims to determine serum pepti...

    Authors: Nai-Jun Fan, Chun-Fang Gao, Guang Zhao, Xiu-Li Wang and Qing-Yin Liu
    Citation: Diagnostic Pathology 2012 7:45
  15. SOX9 as a member of the SOX (SRY [sex determining region Y] box) gene superfamily has been previously demonstrated to be a proto-oncogene in a variety of malignancies. However, the clinical significance of SOX...

    Authors: Xiaodong Guo, Lu Xiong, Ting Sun, Ruiyun Peng, Lin Zou, Haiyan Zhu, Jing Zhang, Hanwei Li and Jingmin Zhao
    Citation: Diagnostic Pathology 2012 7:44
  16. Malignant triton tumor (MTT) is defined as malignant peripheral nerve sheath tumor with rhabdomyoblastic differentiation. Intracranial MTT is extremely rare, and only four cases have been reported in the liter...

    Authors: Li Gong, Xiao-Yan Liu, Wen-Dong Zhang, Xiu-Juan Han, Li Yao, Shao-Jun Zhu, Miao Lan, Yan-Hong Li and Wei Zhang
    Citation: Diagnostic Pathology 2012 7:43
  17. SOX4, as a member of the SRY-related HMG-box (SOX) transcription factor family, has been demonstrated to be involved in tumorigenesis of many human malignancies; however, its role in primary gallbladder carcin...

    Authors: Chengguo Wang, Huadong Zhao, Jianguo Lu, Jikai Yin, Li Zang, Nuan Song, Rui Dong, Tao Wu and Xilin Du
    Citation: Diagnostic Pathology 2012 7:41
  18. The amplification of oncogenes initiated by high-risk human papillomavirus (HPV) infection is an early event in cervical carcinogenesis and can be used for cervical lesion diagnosis. We measured the genomic am...

    Authors: Shaomin Chen, Ziyan Yang, Yun Zhang, Yunbo Qiao, Baoxia Cui, Youzhong Zhang and Beihua Kong
    Citation: Diagnostic Pathology 2012 7:40
  19. We present here an intriguing case of sporadic renal haemangioblastoma occurring in a 61-year-old male. The tumor consisted of nests of polygonal cells and abundant capillary networks. The neoplastic cells gen...

    Authors: Wei-hua Yin, Jian Li and John KC Chan
    Citation: Diagnostic Pathology 2012 7:39
  20. Primary involvement of skeletal muscle is a very rare event in ALK-1 positive anaplastic large cell lymphoma (ALCL). We describe a case of a 10-year old boy presenting with a three week history of pain and a p...

    Authors: Timo Gaiser, Eva Geissinger, Torsten Schattenberg, Hanns-Peter Scharf, Matthias Dürken, Dietmar Dinter, Andreas Rosenwald and Alexander Marx
    Citation: Diagnostic Pathology 2012 7:38
  21. Congenital cystic adenomatoid malformation (CCAM), also named congenital pulmonary airway malformation (CPAM), is a congenital abnormality of lung which is uncommon in adults. Here we present 2 adult cases of ...

    Authors: Anning Feng, Hourong Cai, Qi Sun, Yifen Zhang, Lulu Chen and Fanqing Meng
    Citation: Diagnostic Pathology 2012 7:37
  22. Endolymphatic sac tumor (ELST) is a rare neoplasm which can be encountered sporadically or in Von Hippel-Lindau (VHL) disease. Here we report a sporadic case of ELST in 31-year-old man. Neither the symptoms no...

    Authors: Yan-Hua Sun, Wen Wen, Jun-Hui Wu, Jian-Ming Song, Hong Guan, Kai-Xin Wang and Mei-Quan Xu
    Citation: Diagnostic Pathology 2012 7:36
  23. Robust hardware and software tools have been developed in digital microscopy during the past years for pathologists. Reports have been advocated the reliability of digital slides in routine diagnostics. We hav...

    Authors: László Fónyad, Tibor Krenács, Péter Nagy, Attila Zalatnai, Judit Csomor, Zoltán Sápi, Judit Pápay, Júlia Schönléber, Csaba Diczházi and Béla Molnár
    Citation: Diagnostic Pathology 2012 7:35
  24. Gain of 3q26 is frequently observed in squamous cell carcinomas of mucosal origin, including those originating in the head and neck region. The human telomerase RNA component (hTERC) gene, which is located on ...

    Authors: Yu Liu, Xiao-li Dong, Cheng Tian and Hong-gang Liu
    Citation: Diagnostic Pathology 2012 7:34
  25. Claudin-6 is a candidate tumor suppressor gene in breast cancer, and has been shown to be regulated by DNA methylation and histone modification in breast cancer lines. However, the expression of claudin-6 in b...

    Authors: Xiaoming Xu, Huiying Jin, Yafang Liu, Li Liu, Qiong Wu, Yaxiong Guo, Lina Yu, Zhijing Liu, Ting Zhang, Xiaowei Zhang, Xueyan Dong and Chengshi Quan
    Citation: Diagnostic Pathology 2012 7:33
  26. Breast cancer is the most common cancer and the leading cause of cancer mortality in women worldwide. Hypoxia is an important factor involved in the progression of solid tumors and has been associated with var...

    Authors: Lei Xiang, Zhi-Heng Liu, Qin Huan, Peng Su, Guang-Jun Du, Yan Wang, Peng Gao and Geng-Yin Zhou
    Citation: Diagnostic Pathology 2012 7:32
  27. Breast cancer is the most common malignancy with the highest incidence rates among women worldwide. Triple-negative breast cancer (TNBC) represents the major phenotype of basal-like molecular subtype of breast...

    Authors: Marek Svoboda, Jiri Sana, Martina Redova, Jiri Navratil, Marketa Palacova, Pavel Fabian, Ondrej Slaby and Rostislav Vyzula
    Citation: Diagnostic Pathology 2012 7:31
  28. Assessment of hemoglobin is one of the most reliable indicators for anemia, and is widely used to screen for anemia among pregnant women. The HemoCue® has been widely used for as a point-of-care device for hemogl...

    Authors: Ishag Adam, Samah Ahmed, Mahmoud H Mahmoud and Mohammed I Yassin
    Citation: Diagnostic Pathology 2012 7:30
  29. Digital whole-slide scanning of tissue specimens produces large images demanding increasing storing capacity. To reduce the need of extensive data storage systems image files can be compressed and scaled down....

    Authors: Juho Konsti, Mikael Lundin, Nina Linder, Caj Haglund, Carl Blomqvist, Heli Nevanlinna, Kirsimari Aaltonen, Stig Nordling and Johan Lundin
    Citation: Diagnostic Pathology 2012 7:29
  30. Molecular studies of breast cancer revealed biological heterogeneity of the disease and opened new perspectives for personalized therapy. While multiple gene expression-based systems have been developed, curre...

    Authors: Arvydas Laurinavicius, Aida Laurinaviciene, Valerijus Ostapenko, Darius Dasevicius, Sonata Jarmalaite and Juozas Lazutka
    Citation: Diagnostic Pathology 2012 7:27
  31. Talcosis, a granulomatous inflammation of the lungs caused by inhalation of talcum dust, is a rare form of pneumoconiosis. Besides inhalative occupational exposure, intravenous abuse of adulterated drugs is a ...

    Authors: Andreas Hans Scheel, Daniel Krause, Helmut Haars, Inge Schmitz and Klaus Junker
    Citation: Diagnostic Pathology 2012 7:26
  32. After the introduction of novel effective immunosuppressive therapies, kidney transplantation became the treatment of choice for end stage renal disease. While these new therapies lead to better graft survival...

    Authors: Sean Kirby, Anjali Satoskar, Sergey Brodsky, Amy Pope-Harman, David Nunley, Charles Hitchcock, Ronald Pelletier, Patrick Ross, Tibor Nadasdy and Konstantin Shilo
    Citation: Diagnostic Pathology 2012 7:25
  33. The aim of the study was to assess whether texture analysis is feasible for automated identification of epithelium and stroma in digitized tumor tissue microarrays (TMAs). Texture analysis based on local binar...

    Authors: Nina Linder, Juho Konsti, Riku Turkki, Esa Rahtu, Mikael Lundin, Stig Nordling, Caj Haglund, Timo Ahonen, Matti Pietikäinen and Johan Lundin
    Citation: Diagnostic Pathology 2012 7:22
  34. Seven percent of renal cell carcinoma (RCC) cases are diagnosed as "unclassified" RCC by morphology. Genetic profiling of RCCs helps define renal tumor subtypes, especially in cases where morphologic diagnosis...

    Authors: Gabriela Quiroga-Garza, Sergio Piña-Oviedo, Karime Cuevas-Ocampo, Richard Goldfarb, Mary R Schwartz, Alberto G Ayala and Federico A Monzon
    Citation: Diagnostic Pathology 2012 7:21
  35. Malakoplakia is a disease especially of the urinary tract with typical plaques most frequently observed in the urinary bladder's mucosa. In the context of immunosuppression malakoplakia can also occur in other...

    Authors: Carl Ludwig Behnes, Silke Neumann, Stefan Schweyer and Heinz-Joachim Radzun
    Citation: Diagnostic Pathology 2012 7:20
  36. Concurrent hematologic malignancies are relatively rare. We encountered a case of concurrent acute myeloid leukemia (AML) and T lymphoblastic lymphoma. The bone marrow chromosome analysis showed the karyotype ...

    Authors: Hung Chang, Wen-Yu Chuang, Chien-Feng Sun and Marc R Barnard
    Citation: Diagnostic Pathology 2012 7:19
  37. This paper presents a novel methodology in which the Unified Parkinson's Disease Rating Scale (UPDRS) data processed with a rule-based decision algorithm is used to predict the state of the Parkinson's Disease...

    Authors: Bozena Kostek, Katarzyna Kaszuba, Pawel Zwan, Piotr Robowski and Jaroslaw Slawek
    Citation: Diagnostic Pathology 2012 7:18
  38. An increasing number of publications are suggesting that galectin-3 (Gal-3) and soluble cadherin fragments, such as E-cadherin (sE-CAD) and N-cadherin (sN-CAD), may be considered as cancer markers. Despite the...

    Authors: Joanna Giebultowicz, Malgorzata Polanska-Plachta, Piotr Wroczynski, Piotr Zaborowski and Jerzy A Polanski
    Citation: Diagnostic Pathology 2012 7:17
  39. Classical Hodgkin lymphoma (CHL) is a B-cell lymphoproliferative disorder with a relatively good prognosis. A small but significant percentage of patients, however, will respond poorly to therapy. A recent gen...

    Authors: Jonathan A Harris, Salvia Jain, Qinghu Ren, Alirezah Zarineh, Cynthia Liu and Sherif Ibrahim
    Citation: Diagnostic Pathology 2012 7:12

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