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Citation: Diagnostic Pathology 2010 5(Suppl 1):S21
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Server-based teleconsultation in lung pathology
Citation: Diagnostic Pathology 2010 5(Suppl 1):S18 -
Pathology workflow and the integration of image analysis
Citation: Diagnostic Pathology 2010 5(Suppl 1):S17 -
Changes of texture features due to image compression
Citation: Diagnostic Pathology 2010 5(Suppl 1):S15 -
Image standardization in tissue – based diagnosis
Citation: Diagnostic Pathology 2010 5(Suppl 1):S13 -
Mandatory laboratory quality assurance in connection with image acquisition and analysis – the potential of virtual microscopy
Citation: Diagnostic Pathology 2010 5(Suppl 1):S11 -
Cancer histopathology datasets - development and implementation
Citation: Diagnostic Pathology 2010 5(Suppl 1):S8 -
Information Technology (IT) in Histopathology (HIS)
Citation: Diagnostic Pathology 2010 5(Suppl 1):S6 -
EBV-associated post-transplantation B-cell lymphoproliferative disorder following allogenic stem cell transplantation for acute lymphoblastic leukaemia: tumor regression after reduction of immunosuppression - a case report
Epstein-Barr virus (EBV)-associated B-cell post-transplantation lymphoproliferative disorder (PTLD) is a severe complication following stem cell transplantation. This is believed to occur as a result of iatrog...
Citation: Diagnostic Pathology 2010 5:21 -
Ocular fundus manifestation of two patients following long-term chloroquine therapy: a case report
This report describes the typical manifestations of chloroquine retinopathy with some advanced new technology. A series of examinations were performed on the patients, including the fundus fluorescein angiogra...
Citation: Diagnostic Pathology 2010 5:20 -
Expression and prognostic significance of cox-2 and p-53 in hodgkin lymphomas: a retrospective study
Cyclooxygenase (cox) is the rate-limiting enzyme, which catalyzes the conversion of arachidonic acid into prostaglandins and contributes to the inflammatory process. Cyclooxygenase-2 (cox-2), which is one of t...
Citation: Diagnostic Pathology 2010 5:19 -
Overexpression of c-erb B2 is a negative prognostic factor in anaplastic astrocytomas
The epidermal growth factor receptor (EGFR) family, consisting of four tyrosine kinase receptors, c-erb B1-4, seems to be influential in gliomagenesis. The aim of this study was to investigate EGFR gene amplifica...
Citation: Diagnostic Pathology 2010 5:18 -
Intraductal papilloma of ectopic breast tissue in axillary lymph node of a patient with a previous intraductal papilloma of ipsilateral breast: a case report and review of the literature
The presence of ectopic breast tissue in axillary lymph nodes (ALN) is a benign condition that must be differentiated from primary or metastatic carcinoma. Here we report a patient who underwent excision of en...
Citation: Diagnostic Pathology 2010 5:17 -
Exophytic benign mixed epithelial stromal tumour of the kidney: case report of a rare tumour entity
Mixed epithelial and stromal tumour (MEST) represents a recently described benign composite neoplasm of the kidney, which predominantly affects perimenopausal females. Most tumours are benign, although rare ma...
Citation: Diagnostic Pathology 2010 5:16 -
Ostial plication: a rarely reported cause of sudden death
We report a rare case of ostial plication as a potential cause of sudden death. Very few reports and images are available in the specialized literature regarding this anomaly. Ostial plication may be a source ...
Citation: Diagnostic Pathology 2010 5:15 -
Significance of occult neoplastic cells on tumor metastasis: a case report of gastric cancer
Occult neoplastic cells (ONCs) are the tumor cells floating in the lymph node sinuses, distant from the primary tumor, and supposed to be one of most reliable marker of prognosis.
Citation: Diagnostic Pathology 2010 5:14 -
The relationship of cerb B 2 expression with estrogen receptor and progesterone receptor and prognostic parameters in endometrial carcinomas
Endometrial carcinoma (EC) is the most common malignancy of the female genital tract. Gene alterations and overexpression of various oncogenes are important in tumor development. The human HER 2 neu (c-erbB-2)...
Citation: Diagnostic Pathology 2010 5:13 -
Intranodal palisaded myofibroblastoma (intranodal hemorrhagic spindle cell tumor with amianthoid fibers): a case report and literature review
Intranodal palisaded myofibroblastoma (IPM) is a benign mesenchymal neoplasm originating from smooth muscle cells and myofibroblasts. It is characterized by spindle cells, amianthoid fibers, and by the prolife...
Citation: Diagnostic Pathology 2010 5:12 -
Pulmonary carcinosarcoma initially presenting as invasive aspergillosis: a case report of previously unreported combination
Carcinosarcoma of the lung is a malignant tumor composed of a mixture of carcinoma and sarcoma elements. The carcinomatous component is most commonly squamous followed by adenocarcinoma. The sarcomatous compon...
Citation: Diagnostic Pathology 2010 5:11 -
Comparative proteomic analysis of normal and tumor stromal cells by tissue on chip based mass spectrometry (toc-MS)
In carcinoma tissues, genetic and metabolic changes not only occur at the tumor cell level, but also in the surrounding stroma. This carcinoma-reactive stromal tissue is heterogeneous and consists e.g. of non-...
Citation: Diagnostic Pathology 2010 5:10 -
Utility of immunohistochemical markers in differentiating benign from malignant follicular-derived thyroid nodules
Thyroid nodules are common among adults though only a small percentage is malignant, which can histologically mimic benign nodules. Accurate diagnosis of these thyroid nodules is critical for the proper clinic...
Citation: Diagnostic Pathology 2010 5:9 -
Follicular thyroid carcinoma invades venous rather than lymphatic vessels
Follicular thyroid carcinoma (FTC) tends to metastasize to remote organs rather than local lymph nodes. Separation of FTC from follicular thyroid adenoma (FTA) relies on detection of vascular and/or capsular i...
Citation: Diagnostic Pathology 2010 5:8 -
Automatic measurement of epithelium differentiation and classification of cervical intraneoplasia by computerized image analysis
The feasibility of evaluating an objective grading of cervical intraneoplasia lesions (CIN) is attempted using an automatic computerized system able to measure several valuable parameters with special referenc...
Citation: Diagnostic Pathology 2010 5:7 -
Intracellular and extracellular rhomboid shaped crystalline inclusions in a case of IgG lambda restricted plasma cell myeloma: a case report and review of the literature
The presence of crystalline inclusions in plasma cell myeloma is a rare phenomenon and cases have been reported with rod, needle, and rectangular shaped crystals. Here, we present a case of IgG lambda restrict...
Citation: Diagnostic Pathology 2010 5:6 -
Melanotic oncocytic metaplasia of the nasopharynx as a benign mimicker of malignant melanoma: a case report
Melanotic variant of oncocytic metaplasia of the nasopharynx is an extremely rare condition.
Citation: Diagnostic Pathology 2010 5:5 -
Pancreatic intraductal papillary mucinous neoplasm with concomitant heterotopic pancreatic cystic neoplasia of the stomach: a case report and review of the literature
A 60-year-old Caucasian male underwent a total pancreatectomy for a mixed type pancreatic intraductal papillary mucinous neoplasm (IPMN) arising in the main and secondary pancreatic ducts. During surgery, a su...
Citation: Diagnostic Pathology 2010 5:4 -
Identification of tissue of origin in carcinoma of unknown primary with a microarray-based gene expression test
Carcinomas of unknown primary (CUP) represent approximately 3%-5% of malignant neoplasms. Identifying the tissue of origin (TOO) in these tumors allows for more specific treatment and improves outcomes. Howeve...
Citation: Diagnostic Pathology 2010 5:3 -
Malignant peripheral nerve sheath tumor associated with neurofibromatosis type 1, with metastasis to the heart: a case report
A rare case is presented of a 61-year-old man with a malignant peripheral nerve sheath tumor associated with neurofibromatosis type 1, with metastasis to the heart. The primary tumor originated in the right th...
Citation: Diagnostic Pathology 2010 5:2 -
Usefulness of molecular biology performed with formaldehyde-fixed paraffin embedded tissue for the diagnosis of combined pulmonary invasive mucormycosis and aspergillosis in an immunocompromised patient
Immunocompromised patients who develop invasive filamentous mycotic infections can be efficiently treated if rapid identification of the causative fungus is obtained. We report a case of fatal necrotic pneumon...
Citation: Diagnostic Pathology 2010 5:1 -
Giant cell tumor-like lesion of the urinary bladder: a report of two cases and literature review; giant cell tumor or undifferentiated carcinoma?
Giant cell tumor, excluding its prototype in bone, is usually a benign but local aggressive neoplasm originating from tendon sheath or soft tissue. Malignant behavior is uncommon. Visceral organ involvement in...
Citation: Diagnostic Pathology 2009 4:48 -
The journey of Diagnostic Pathology in 2009, perspectives for 2010
Editorial: The journey of Diagnostic Pathology in 2009, perspectives for 2010
Citation: Diagnostic Pathology 2009 4:47 -
RNA interference as a gene silencing therapy for mutant MYOC protein in primary open angle glaucoma
Primary open-angle glaucoma (POAG) is the most common form of glaucoma which is an irreversible blind leading disease and lacks effective remedies. In recent years, POAG has been linked to the gene MYOC encoding ...
Citation: Diagnostic Pathology 2009 4:46 -
Embolization of Cyanoacrylate glue in systemic circulation in a case of hepatocellular carcinoma: an autopsy report
We report a case of embolism of the sclerosant dye with subsequent formation of foreign-body giant cell reaction within the veins of pulmonary and portal circulation in an autopsy case of hepatocellular carcin...
Citation: Diagnostic Pathology 2009 4:45 -
Fatal hemopericardial tamponade due to primary pericardial mesothelioma: a case report
Primary mesothelioma of the pericardium comprises less than 1% of all mesothelioma cases. Its typical presentation is insidious, with nonspecific signs and symptoms, and usually results in heart failure due to...
Citation: Diagnostic Pathology 2009 4:44 -
A case of non-invasive serous adenocarcinoma at unilateral fimbria with spread to the peritoneal/uterine cavity: case report
Recently, fimbriae have been identified as a possible arising site for the pelvic serous carcinoma (PSC) both in BRCA-positive and BRCA-negative women. Although non-invasive (intraepithelial) serous adenocarci...
Citation: Diagnostic Pathology 2009 4:43 -
Localized early mesenteric Castleman's disease presenting as recurrent intestinal obstruction: a case report
Primary neoplasms of the mesentery are very rare. They are usually of mesenchymal origin and include desmoid tumor, lipoma, liposarcoma, and fibrosarcoma. Metastatic carcinomas and lymphoma are more common. We...
Citation: Diagnostic Pathology 2009 4:42 -
Altered PTEN expression; a diagnostic marker for differentiating normal, hyperplastic and neoplastic endometrium
Different molecular alterations have been described in endometrioid endometrial carcinoma (EECA). Among them the most frequently altered is loss of the PTEN protein, a tumor suppressor gene. The purpose of thi...
Citation: Diagnostic Pathology 2009 4:41 -
An unusual suicidal death by automobile antenna: a case report
Worldwide, over one million people commit suicide every year. In the United States, the majority of these cases consist of gunshot wounds, hangings, and drug overdoses. Nevertheless, on rare occasions will ind...
Citation: Diagnostic Pathology 2009 4:40 -
Association between the methylenetetrahydrofolate reductase C677T polymorphism and hepatocellular carcinoma risk: a meta-analysis
Methylenetetrahydrofolate reductase (MTHFR) is a key enzyme in the metabolism of folate. The non-synonymous single nucleotide polymorphism (nsSNP), C677T (Ala>Val, rs1801133), has been verified to impair enzym...
Citation: Diagnostic Pathology 2009 4:39 -
CD10 expression in urothelial carcinoma of the bladder
CD10 antigen is a 100-kDa-cell surface zinc metalloendopeptidase and it is expressed in a variety of normal and neoplastic lymphoid and nonlymphoid tissues. The aim of this study was to evaluate CD10 expressio...
Citation: Diagnostic Pathology 2009 4:38 -
Mixed hepatoblastoma and teratoma of the liver in a 3-year-old child: a unique combination and clinical challenge
Primary liver tumors in children are rare with malignant hepatoblastoma being the most common neoplasm. In this report, we describe the diagnosis and clinical management of a large liver tumor in a 3-year-old ...
Citation: Diagnostic Pathology 2009 4:37 -
Evaluation of 7q31 region improves the accuracy of EGFR FISH assay in non small cell lung cancer
Increase of EGFR gene copy number consequent to gene amplification and/or polysomy of chromosome 7 has been significantly associated with better clinical outcome in Non Small Cell Lung Cancer (NSCLC) patients tre...
Citation: Diagnostic Pathology 2009 4:36 -
Utility of a dual immunostain cocktail comprising of p53 and CK20 to aid in the diagnosis of non-neoplastic and neoplastic bladder biopsies
Distinction between non-neoplastic and neoplastic bladder lesions is therapeutically and prognostically important. Our objective is to describe the use of double immunohistochemistry (DIHC) for p53+CK20 as a t...
Citation: Diagnostic Pathology 2009 4:35 -
Mast cell gastritis: Children complaining of chronic abdominal pain with histologically normal gastric mucosal biopsies except for increase in mast cells, proposing a new entity
Mast cells reside within the connective tissue of a variety of tissues and all vascularized organs. Since 1996, few studies have been performed on mast cell density in gastrointestinal biopsies, mainly in adul...
Citation: Diagnostic Pathology 2009 4:34 -
Collagenofibrotic Glomerulopathy: Three Case Reports in Brazil
We are reporting the first Collagenofibrotic Glomerulopathy (CG) in South America. So, this collagen type III glomerulopathy is not limited to Japan but may be found throughout the world.
Citation: Diagnostic Pathology 2009 4:33 -
Juvenile pleomorphic adenoma of the cheek: a case report and review of literature
Pleomorphic adenoma, also called benign mixed tumor, is the most common tumor of the salivary glands. About 90% of these tumors occur in the parotid gland and 10% in the minor salivary glands. The most common ...
Citation: Diagnostic Pathology 2009 4:32 -
Genotype distribution of cervical human papillomavirus DNA in women with cervical lesions in Bioko, Equatorial Guinea
The HVP vaccine is a useful tool for preventing cervical cancer. The purpose of this study is to determine the most frequent HPV genotypes in Equatorial Guinea in order to develop future vaccination strategies...
Citation: Diagnostic Pathology 2009 4:31 -
Cylindroma of the breast: a case report and review of the literature
Cylindroma of the breast is a very rare lesion which is morphological and immunophenotypically identical to benign dermal cylindroma. We report a breast cylindroma in a previously healthy 62 year old female de...
Citation: Diagnostic Pathology 2009 4:30 -
Histopathological study of lesions of the caruncle: a 15-year single center review
The caruncle is a modified cutaneous tissue located at the inner canthus that contains hair follicles, accessory lacrimal glands, sweat glands and sebaceous glands. These different types of tissues can give ri...
Citation: Diagnostic Pathology 2009 4:29 -
Miescher's granulomatosis (granulomatosis disciformis chronica et progressiva) in a non-diabetic patient – case report
Necrobiosis lipoidica diabeticorum is a rare disease of unclear etiology, that occurs in about 1% of diabetic patients.
Citation: Diagnostic Pathology 2009 4:28
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2022 Citation Impact
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2.7 - 5-year Impact Factor
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