Prevention of an additional surgery for regional lymphadenectomy in melanoma: rapid intraoperative immunostaining of sentinel lymph node imprint smears

Table 3 Comparison of studies evaluating melanoma SLNs intraoperatively

Authors	Intraoperative evaluation	Sensitivity (%)	Specificity (%)
Gibbs et al [20A]	FS	43	100
Clary et al [20B]	FS	56	100
Tanis et al [20C]	FS	47	100
Stojadinovic [20]	FS	59	100
Creager et al [21]	IS	38	100
Eudy et al [23]	FS with IHC	86	97
Current study	ICIS	90	100

FPTS, formalin-fixed paraffin-embedded tissue section; FS, frozen section, ICIS, immunocytochemical evaluation of imprint smears with 'MCW melanoma cocktail' (mixture of Melan- A, MART- 1, & tyrosinase); , IHC, immunohistochemistry with cocktail of Melan- A, HMB-45, & tyrosinase); IS, imprint smear; SLNs, sentinel lymph nodes; MM, melanoma metastases.

ISSN: 1746-1596