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Table 1 Malignant tumor in previous blind eyes

From: Malignancy in the blind painful eye – report of two cases and literature review

Authors

Patient

Eye

Signs/Symptoms

Suspicious malignancy

Treatment

Pathologic diagnosis

Follow-up

Ten Thije 6

66-year-old, man

RE

Exophthalmos

Yes

Exenteration

Large-cell sarcoma

Death few months after diagnostic

Sarma et al 5

62-year-old, man

LE

Progressive proptosis, eye pain, left orbit mass

Yes

Exenteration

Extrascleral Uveal melanoma

No follow-up reported

Nelson & Kincaid 4

70-year-old, man

LE

dark inferonasal and superiorly conjunctival mass, mass in the anterior chamber

Yes

Exenteration

Extrascleral Uveal melanoma (ciliary body)

Pulmonary and bone metastasis, death 1 year after diagnostic

Nelson & Kincaid 4

79-year-old, man

RE

eye pain, black exophytic subconjunctival mass

Yes

Exenteration

Extrascleral Uveal melanoma

Liver metastasis 8 months later, death 14 months after diagnostic

Loeffler et al 3

66-year-old, man

RE

eye pain

No

Enucleation

Malignant tumor of the retinal pigment epithelium

No death or metastasis 1 year after enucleation

Edelstein et al 2

79-year-old, woman

RE

eye pain, exophthalmos

No

Enucleation

Presumed Adenocarcinoma of the retinal pigment epithelium with staphyloma

No follow-up reported

Tripathi et al 7

45-year-old

RE

Eye pain

No

Enucleation

Uveal melanoma

No follow-up reported

Pereira et al

57-year-old, man

LE

eye pain, endophthalmitis, orbital cellulites

No

Enucleation

Extrascleral Uveal melanoma

No signs of metastatic disease after four years of follow-up

Pereira et al

54-year-old, man

LE

eye pain

No

Enucleation

Extranodal lymphoma of uveal tract with extra ocular extension

Lost to follow-up after six years