Skip to main content

Table 1 Laboratory Presentation

From: Ectopic corticotropin-releasing hormone (CRH) syndrome from metastatic small cell carcinoma: a case report and review of the literature

AT PRESENTATION (Normal Range)

VALUE

Serum Potassium (3.8-5.2 mEq/l)

2.1

Serum HCO3 (21-32 mEq/l)

42

Plasma Glucose (mg/dl)

339

Morning Serum Cortisol (06:15) (4.0-32 μg/dl)

111.1

ENDOCRINE WORK-UP (Normal Range)

1 mg Overnight Dexamethasone Supression Test (Normal cortisol < 1.8 μg/dl)

116.7

48 hour High Dose Dexamethasone Supression Test (Normal cortisol < 1.8 μg/dl)

109.8

24 hour Urine Free Cortisol (0 to 50 μg)

16 575

Plasma ACTH (10-46 pg/ml)

278

Plasma CRHa (0-10 pg/ml)

10

Plasma Chromogranin A (0-5.0 nmol/l)

26

Serum Carcinoembryonic antigen (0-5.0 ng/ml)

10.59

Serum Calcitonin (0-5 pg/ml)

< 2.0

Serum Serotonin (0-420 ng/ml)

156

Plasma Metanephrine (0-62 pg/ml) and

Normetanephrine (0-145 pg/ml)

12

37

Serum Gastrin (13.0-115.0 pg/ml)

280

24 hr Urinary 5-HIAA (0-8.0 mg)

6.7

  1. Abbreviations: ACTH, Adrenocorticotropic Hormone; CRH, Corticotropin Releasing Hormone, 5-HIAA, 5-hydroxy-indoleacetic acid
  2. aCRH assay is a plasma based test by which Corticotropin Releasing Factor is measured by direct radioimmunoassay (Inter Science Institute, Inglewood, CA).