Table 1 Frequencies of methylation of analyzed genes in PB and breast tumors.
GENE | Chromosomal region targeted by assay * | Number of paired samples used/excluded** | Methylated in both blood and tumor Sample no. (%) | Methylated only tumor*** | Methylated only PBL Sample no. (%) |
|---|---|---|---|---|---|
BRCA1 | chr17:41, 277, 382-41, 277, 409 | 75/6 | 3 (4.3%) | 23% | 3 (4.3%) |
APC | chr5:112, 073, 470-112, 073, 516 | 75/3 | 3 (4.1%) | 83% | 2 (2.7%) |
RASSF1A | chr3:50, 377, 755-50, 378, 089 | 75/2 | 0% | 97% | 0 |