Factor | Unadjusted odds ratio and 95% confidence interval | ALNM negative (n = 94) | ALNM positive (n = 116) | P value |
---|---|---|---|---|
Age (yr), mean ± SD | - | 55.8 ± 12.4 | 51.7 ± 13.3 | 0.020 |
Age groups (yr) | Â | Â | Â | Â |
<50 | 0.70 (0.40-1.23) | 31/94 (33.0%) | 48/116 (41.4%) | Â |
≥50 |  | 63/94 (67.0%) | 68/116 (58.6%) | 02.12 |
Tumor size (mm) | Â | Â | Â | Â |
T1a (0-5.0) | Reference | 6/93 (6.5%) | 3/115 (2.6%) | 0.001 |
T1b (5.1-10) | 1.54 (0.31-7.72) | 13/93 (14.0%) | 10/115 (8.7%) | Â |
T1c (10.1-20.0) | 1.27 (0.29-5.65) | 33/93 (35.5%) | 21/115 (18.3%) | Â |
T2 (20.1-50.0) | 3.35 (0.79-14.21) | 37/93 (39.8%) | 62/115 (53.9%) | Â |
T3-T4 > 50 | 9.50 (1.65-55.0) | 4/93 (4.3%) | 19/115 (16.5%) | Â |
Tumor size >20 mm | 3.02 (1.70-5.36) | 41/93 (44.1%) | 81/115 (70.4%) | <0.001 |
Histologic grade | Â | Â | Â | Â |
1 | Reference | 19/87 (21.8%) | 24/111 (21.6%) | Â |
2 | 0.68 (0.32-1.47) | 37/87 (42.5%) | 32/111 (28.8%) | 0.332 |
3 | 1.40 (0.67-2.96) | 31/87 (35.6%) | 55/111 (49.5% | 0.371 |
Bilateral disease | 1.03 (0.37-2.88) | 7/92 (7.6%) | 9/115 (7.8%) | 0.954 |
Multicentric disease | 2.03 (1.07-3.87) | 18/93 (19.4%) | 38/116 (32.8%) | 0.030 |
Lymphovascular invasion | 16.69 (8.30-33.56) | 16/91 (17.6%) | 89/114 (78.1%) | <0.001 |
Microcalcification | 1.69 (0.93-3.08) | 24/90 (26.7%) | 43/113 (38.1%) | 0.087 |
Epithelial hyperplasia | 2.43 (1.37-4.31) | 32/89 (36.0%) | 64/111 (57.7%) | 0.002 |
Necrosis | 2.12 (1.10-4.08) | 17/89 (19.1%) | 38/114 (33.3%) | 0.024 |
In situ carcinoma | 2.60 (1.32-5.12) | 63/92 (68.5%) | 96/113 (85.0%) | 0.005 |
Perineural invasion | 3.02 (1.70-5.36) | 22/91 (24.2%) | 50/114 (43.9%) | 0.003 |