Invasive behavior of ulcerative colitis-associated carcinoma is related to reduced expression of CD44 extracellular domain: comparison with sporadic colon carcinoma

Table 3 Comparison of histologic type between mucosa and deeper parts (submucosa or deeper) of cancer lesion

		UC-associated (n= 15)	Sporadic (n= 75)	P value
Mucosa area	Deeper area
Well	Well	2	25
Well	Moderately	5	18
Well	Poorly	2	0
Moderately	Moderately	1	20
Moderately	Poorly	3	7
Poorly	Poorly	2	5	0.0062*
Poorer differentiation in deep parts**		10 (66.7%)	25 (33.3%)	0.033*

UC - ulcerative colitis; n - number of cases.
* χ² test,
** Cases which were shown to be well differentiated at the mucosa and moderately to poorly differentiated at the deep areas, and showed moderately differentiated at mucosa and poorly differentiated at the deep areas.

ISSN: 1746-1596