Table 3 Results of the immunohistochemical analyses of the proliferation markers
Case no. | Mitoses/10HPF | Mitotic index | Ki-67 /MIB-1 | PHH3 mitoses /10HPF | PHH3 index | TIIα | Survivin | Mitosin |
|---|---|---|---|---|---|---|---|---|
1 | N.D.1 | N.D. | 6.8 | 1 | 0.5 | 1.8 | 2 | 2.4 |
2 | 0 | 0 | 3.5 | 1 | 1.7 | 2.5 | 2.7 | 8.5 |
3 | 15 | 0.9 | 6.8 | 19 | 0.9 | 10.8 | 5.3 | 3.4 |
4 | 1 | 0.6 | 9.2 | 18 | 0.9 | 7.9 | 7.5 | 8.6 |
5 | 0 | 0 | 19.0 | 6 | 2.2 | 0 | 5.8 | 3.6 |
6 | 2 | 0.4 | 9.2 | 2 | 0.6 | 2 | 3.4 | 3.1 |
7 | 0 | 0 | 1.0 | 0 | 0.0 | 0.8 | 0.3 | 0 |
8 | 1 | 0.6 | 7.9 | 1 | 0.8 | 2.7 | 3.3 | 3.5 |
9 | 0 | 0 | 5.0 | 1 | 0.2 | 0 | 2.4 | 2.5 |
10 | 0 | 0 | 2.1 | 3 | 0.6 | 0 | 1.9 | 1.8 |
11 | N.D. | N.D. | 6.4 | 10 | 1.3 | 25 | 3.7 | 1.5 |
12 | 0 | 0 | 4.2 | 4 | 1.0 | 4 | 2.7 | 1.9 |
13 | N.D. | N.D. | 4.4 | 4 | 0.6 | 1.8 | 1.2 | 1.1 |
14 | N.D. | N.D. | 8.5 | 8 | 0.8 | 5 | 2.6 | 3.4 |
15 | 6 | 0.5 | 22.2 | 9 | 1.1 | 8.2 | 6 | 3.8 |
16 | N.D. | N.D. | 8.6 | 1 | 0.5 | 6.1 | 2.5 | 8 |
17 | 1 | 0.7 | N.D. | N.D. | N.D. | 4.5 | 3.8 | 2.9 |
18 | N.D. | N.D. | 15.0 | 5 | 1.9 | 6 | 4.4 | 2.7 |
19 | 0 | 0 | 20.0 | 2 | 0.4 | 5.4 | 2.3 | 1.4 |
20 | N.D. | N.D. | 3.2 | 1 | 0.1 | 1.4 | 1.5 | N.D. |
21 | N.D. | N.D. | 16.4 | 30 | 1.1 | 6.9 | 3.5 | 4.5 |
22 | 2 | 0.5 | 4.0 | 5 | 0.8 | 3.7 | 3.5 | 1.2 |
23 | 1 | 0.8 | 12.9 | 15 | 2.0 | 0 | 6.1 | 2.7 |
24 | N.D. | N.D. | 4.9 | 16 | 1.5 | 2 | 2 | 2 |
25 | 0 | 0 | 16.5 | 24 | 1.7 | 11 | 8.9 | 5.1 |
26 | 0 | 0 | 10.2 | 19 | 0.6 | 6.3 | 2.6 | N.D. |
27 | 13 | 0.7 | 21.0 | 37 | 2.7 | 13.5 | 9.6 | 9.5 |
Median | 0.5 | 0.2 | 8.2 | 5 | 0.8 | 4 | 3.3 | 2.9 |
Minimum | 0 | 0 | 1 | 0 | 0 | 0 | 0.3 | 0 |
Maximum | 15 | 0.9 | 22.2 | 37 | 2.7 | 25 | 9.6 | 9.5 |
Mean | 2.3 | 0.3 | 9.6 | 9.3 | 1.0 | 5.2 | 3.8 | 3.6 |
Std. deviation | 4.5 | 0.3 | 6.3 | 10.0 | 0.7 | 5.4 | 2.3 | 2.5 |
Variance | 20.2 | 0.1 | 39.6 | 100.2 | 0.5 | 28.9 | 5.2 | 6.4 |