| Age, years | Gender | Kidney disease | Transplant type | Time, mos | Sirolimus trough levels, mean(range), ng/ml | Other immuno-suppressants | Clinical radiological presentation | Biopsy type | Pathological findings |
---|---|---|---|---|---|---|---|---|---|---|
1* | 49 | M** | DM1 | K/Cad | 11 | 11.7(6.2-18.7) | C/P | Bilateral mass-like consolidations | EB | ND |
2 | 25 | F | DM1 | K/Cad | 20 | Â | C/MY/D | Patchy bilateral consolidations | EB | BCLPD |
3 | 71 | M | PCKD | K/Cad | 36 | Â | C/D | Mediastinal lymphadenopathy | EB LNB | DLBCL |
4 | 58 | F | DM2 | K/Cad | 5 | 8.8(4.0-17.1) | C/P | Respiratory failure Diffuse ground glass opacities | EB THB | Hemorrhage |
5 | 47 | F | HTN | K/Cad | 210 | Â | C/MY/P | Respiratory failure, loculated pneumonia | EB | Necrosis Fibrin |
6 | 72 | M | DM2 | K/Cad | 20 | 4.8(2.0-8.2) | C/P | Spiculated lung lesion | NB | SQC |
7 | 77 | M | Â | K/Cad | 116 | Â | C/D | Pulmonary nodule | EB | SQC |
8 | 71 | M | pANCA | K/Cad | 10 | 15.1 | C/P | Right lower lobe mass | EB | ND |
 |  |  |  |  |  |  |  | Diffuse ground glass opacities |  |  |
9 | 48 | F | NA | K/Cad | 32 | NA | MY/P | Left lower lobe nodule | EB | Necrosis Fibrin |
10 | 39 | M | GN | K/Cad | 80 | 10.2(8.1-11.8) | C/P | Respiratory failure, diffuse ground glass opacities with crazy paving pattern | THB EB | Hemorrhage PAP OP |
11 | 45 | F | NA | K/Cad, LR | 345 | Â | C/P | Collapsed lung, pneumonia | EB | OP |
12 | 58 | F | HTN | K/Cad | 24 | 19.7 | C/P | Respiratory failure, diffuse ground glass opacities | EB THB | Hemorrhage |
13 | 44 | F | DM2 | K/LR | 36 | 5.3(3.2-6.9) | C/P | Mediastinal lymphadenopathy, patchy ground glass opacities | EB | ND |
14 | 46 | M | WG | K/LR | 175 | Â | C/MY/P | Diffuse ground glass opacities, lung nodules | EB NB | Hemorrhage Capillaritis |
15 | 49 | F | DM | K | 73 | 8.1(4.3-11.6) | C/P | Bilateral ground glass opacification with right lower lobe consolidation | EB | OP |
16 | 34 | F | DM1 | KP/Cad | 19 | 4.2(2.4-6.7) | C/P | Respiratory failure, diffuse ground glass opacities | THB | DAD Hemorrhage |
17 | 43 | M | DM1 | KP | 41 | 4.4 | C/P | Nodular right lower lobe infiltrate | EB | ND |
18 | 69 | M | DM2 | K/LU | 4 | 11.0(5.0-14.9) | C/P | Bilateral lung nodules and mediastinal lymphadenopathy | NB | BCLPD |
19 | 71 | M | IgA | K/LR | 114 | Â | C/P | Dyspnea, diffuse ground glass opacities | EB | PAP |
20 | 60 | M | GN | K/LR | 89 | Â | C/MY/D | Lung nodule | EB | ND |
21 | 65 | M | Â | K/LR | 41 | 6.8(2.8-12.0) | MA/P | Bilateral hypermetabolic lung nodules | THB | PJ granulomas |
22 | 60 | M | GN | K/LR | 66 | Â | C/P | Lung mass | THB | ADC |
23 | 52 | M | DM1 | KP/Cad | 73 | Â | C/P | Lung mass | EB | SQC |
24 | 34 | M | GN | K/Cad | 38 | 10.2(6.1-14.3) | C/P | Bilateral ground glass opacities Loculated right sided pleural effusion | EB | Fibrin Necrosis |
25 | 36 | F | NA | K | 180 | Â | C/P | Bilateral lung nodules, lymphadenopathy | THB NB | LYG |
26 | 62 | M | IN | K/LR | 115 | Â | C/P | Lung mass | NB | ADC |
27 | 53 | M | PCKD | K/LU | 61 | 2.0 | MA/P | Lung nodule, pleural effusion | EB | ND |
28 | 32 | M | CR | K/LU | 220 | 8.6(4.4-13.2) | C/MA/P | Dyspnea, patchy ground glass opacities | EB | OP |