Table 4 Associations between the factor 1 and 2 scores and the conventional categories of the ductal carcinoma of the breast
n | i-Grade-High | SATB1/HIF-1α-High | HER2-High | p53-High | p16-High | |
|---|---|---|---|---|---|---|
Number of patients 109 | ||||||
Age group | n.s. | n.s. | p < 0.03 | p < 0.003 | n.s. | |
Age < 55 year | 52 | 19 (37) | 28 (54) | 20 (38) | 39 (75) | 28 (54) |
Age > 55 year | 57 | 17 (30) | 29 (51) | 34 (60) | 27 (47) | 30 (53) |
Histological grade | p < 0.00001 | n.s. | n.s. | n.s. | n.s. | |
1 | 19 | 0 (0) | 12 (63) | 10 (53) | 7 (37) | 12 (63) |
2 | 44 | 9 (21) | 26 (59) | 27 (61) | 30 (68) | 22 (50) |
3 | 46 | 27 (59) | 19 (41) | 17 (37) | 29 (63) | 24 (52) |
T | n.s. | n.s. | n.s. | n.s. | n.s. | |
1 | 58 | 16 (28) | 31 (53) | 33 (57) | 37 (64) | 27 (47) |
2 | 51 | 20 (44) | 26 (51) | 21 (41) | 29 (57) | 31 (61) |
N | n.s. | n.s. | n.s. | n.s. | n.s. | |
0 | 66 | 25 (38) | 36 (55) | 30 (45) | 40 (61) | 35 (53) |
1 | 43 | 11 (26) | 21 (49) | 24 (56) | 26 (60) | 23 (53) |
Intrinsic subtype | p < 0.0001 | n.s. | p < 0.00001 | n.s. | p < 0.002 | |
Luminal A | 43 | 0 (0) | 29 (67) | 25 (58) | 23 (53) | 26 (60) |
Luminal B | 27 | 7 (26) | 10 (37) | 10 (37) | 19 (70) | 8 (30) |
Luminal B HER2+ | 15 | 6 (40) | 7 (47) | 12 (80) | 10 (67) | 8 (53) |
HER2+ | 6 | 6 (100) | 2 (33) | 6 (100) | 2 (33) | 1 (17) |
Triple-negative | 18 | 17 (94) | 9 (50) | 1 (6) | 12 (67) | 15 (83) |