Diagnostic Pathology

Table 1 The correlation between the expression of HIF-2 alpha and BCRP, the clinicopathological parameter

From: Hypoxia-inducible factor-2a is associated with ABCG2 expression, histology-grade and Ki67 expression in breast invasive ductal carcinoma

	Patients n (%)	HIF-2 alpha expression			P value
		negative	low	high
ABCG2 expression					0.001*
negative	26	8	17	1
low	97	12	58	27
high	73	5	39	29
Age					0.053
≤ 50 years	80	10	54	16
> 50 years	116	15	60	41
Histology-type					0.285
IDC	155	22	86	47
IDC with others	41	3	28	10
Histology-grade					0.029*
G1/G2	143	16	78	49
G3	53	9	36	8
Tumour size					0.601
≤2.0 cm	97	13	53	31
> 2.0 cm	99	12	61	26
LNM					0.808
-	103	13	58	32
+	93	12	56	25
ER					0.544
-/+	96	10	59	27
++/+++	100	15	55	30
PR					0.343
-/+	128	14	79	35
++/+++	68	11	35	22
HER2					0.923
-/+	138	18	81	39
++/+++	58	7	33	18
Ki67					0.043*
Positive ≤50%	154	20	83	51
Positive > 50%	42	5	31	6
Clinical stage					0.538
Stage I	60	7	33	20
Stage IIa and IIb	86	13	47	26
StageIIIa and IIIb	50	5	34	11

P values were evaluated by chi-square test or the Fisher's exact test. *P < 0.05

Back to article page

ISSN: 1746-1596

Contact us

Submission enquiries: journalsubmissions@springernature.com