Sporadic haemangioblastoma of the kidney with rhabdoid features and focal CD10 expression: report of a case and literature review

Table 2 Clinicopathological characteristics of the reported sporadic hemangioblastomas in the kidney

Case	Age(y)/Sex	Gross features	Histological features				Immunohistochemical staining		Treatment/Follow-up(y)
			Cytoplasm	Nuclear	Necrosis	Stromal fibrosis	Diffuse	Focal
1(ref.4)	71/female	Solid with scattered cystic spaces; located in right kidney	Amphophilic to clear	Round with delicate chromatin; lack of mitoses	Absent	Present	a-inhibin	Vimentin, S100, SMA, MSA, calponin	NP/AW/9
2(ref.5)	58/male	Solid with a cystic cavity; located in right kidney	Eosinophilic	Mildly to highly pleomorphic; lack of mitoses	Absent	Present	a-inhibin, S100, NSE, GLUT1		NP/AW/2
3(ref.5)	55/female	Solid; located in right kidney	Eosinophilic; variable-sized hyaline globules were found	Mildly to highly pleomorphic; very sparse mitoses	Present	Present	a-inhibin, S100, NSE, GLUT1		NP/AW/4
4(ref.6)	64/male	Solid; located in left kidney	Weakly eosinophilic	Enlarged and slightly atypical; lack of mitoses	Absent	Present	S100, NSE, Vimentin	EMA, a-inhibin	pNP/AW/4
5(present case)	61/male	Solid; located in right kidney	Eosinophilic; exhibiting a rhabdoid phenotype	Mildly to highly pleomorphic; intranuclear cytoplasmic pseudoinclusions were present; sparse mitoses	Present	Present	a-inhibin, S100, NSE, EGFR	CD10, EMA	NP/AW/1

ISSN: 1746-1596