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Figure 3 | Diagnostic Pathology

Figure 3

From: Genomic amplification patterns of human telomerase RNA gene and C-MYC in liquid-based cytological specimens used for the detection of high-grade cervical intraepithelial neoplasia

Figure 3

ROC and DFI curves for aberrant cell percentage and maximum GCN of TERC and C-MYC gain for CIN2+ diagnosis. A: Plots of sensitivity vs. 1-specificity at cut-off values of the percentage of aberrant cells and of maximum GCN for the TERC and C-MYC tests. B: Plots of DFI vs. cut-off values of the percentage of aberrant cells of the TERC and C-MYC tests. C: Plots of DFI vs. cut-off values at maximum GCN of the TERC and C-MYC tests. In A, B and C, blue diamonds indicate the results of TERC gain at cut-off values of aberrant cell percentage ranging from 0% to 100%; pink squares indicate the results of C-MYC gain at cut-off values of aberrant cell percentage ranging from 0% to 100%; orange diamonds indicate the results of TERC gain at cut-off values of GCN ranging from 1 to 23; slate green squares indicate the results of C-MYC gain at cut-off values of GCN ranging from 1 to 13.

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Diagnostic Pathology

ISSN: 1746-1596

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