From: Mechanisms of cyst formation in metastatic lymph nodes of head and neck squamous cell carcinoma
Environment | Environmental condition for malignant cells | Proliferation rate | Acquisition of mutations | Tumor presentation |
---|---|---|---|---|
Primary site | Suitable environment | High | High | Low expression of intrinsic properties |
Lymph node | Strong immunologic host response, Harsh environment | Low | Low | Silent presentation of tumor and expression of intrinsic properties |