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Figure 5 | Diagnostic Pathology

Figure 5

From: Invasive salivary duct carcinoma ex pleomorphic adenoma of the parotid gland: a teaching case giving rise to the genuine diagnostic difficulty on an inadequate cytology specimen

Figure 5

Myoepithelial markers analysis of the invasive SDC ex PA in immunohistochemistry. (A, B) The carcinoma cells were negative for S-100 protein (A) and p63 (B). By contrast, the myoepithelial cells of the PA and ID components were positive for S-100 protein and p63 (A-B, rt. side) (Original magnification × 200, Bar = 100 μm). However, as to the ID components, the neoplastic-like myoepithelial cells (arrowheads) having mildly enlarged and hyperchromatic nuclei were sometimes negative for both of S-100 protein (A, inset) and p63 (B, inset) (Original magnification × 400, Bar = 50 μm). Also, the lost of myoepithelial cells was focally apparent in the ID components (A-B, lt. side).

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