Figure 5From: Analysis of aberrant methylation on promoter sequences of tumor suppressor genes and total DNA in sputum samples: a promising tool for early detection of COPD and lung cancer in smokersBiomarkers obtained in COPD patients evaluated in 2012 as negative LC (−LC) and positive LC (+LC). Figure shows as a percentage H-S-Freq (High Smoke Frequency), H-GOLD (High GOLD: GOLD > 2) and methylation on p16, CDH1 and MGMT. * P < 0.05 respect to -LC group.Back to article page