Table 3 Cox proportional hazards model for colorectal cancer specific survival related to MSI screening status and beta-catenin overexpression in the full cohort and in stage III-IV disease
Full cohort | Stage III-IV disease | |||||
|---|---|---|---|---|---|---|
HR(95% CI) | p-value | N(events) | HR(95% CI) | p-value | n(events) | |
Univariable | Univariable | |||||
MSS | 1,00 | 0,010** | 438(157) | 1,00 | 0,036* | 201(122) |
MSI | 0,50(0,29-0,84) | 77(15) | 0,46(0,23-0,95) | 23(8) | ||
Multivariable | Multivariable | |||||
MSS | 1,00 | 0,010* | 389(137) | 1,00 | 0,011* | 185(107) |
MSI | 0,46(0,25-0,84) | 73(13) | 0,33(0,14-0,78) | 20(6) | ||
Univariable | Univariable | |||||
Bata-catenin low | 1,00 | 0,056 | 251(96) | 1,00 | 0,063 | 112(72) |
Bata-catenin High | 0,75(0,56-1,01) | 276(86) | 0,73(0,52-1,02) | 122(66) | ||
Multivariable | Multivariable | |||||
Bata-catenin low | 1,00 | 0,031* | 223(80) | 1,00 | 0,036* | 98(60) |
Bata-catenin High | 0,70(0,51-0,97) | 247(75) | 0,67(0,46-0,97) | 113(57) | ||