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Figure 7 | Diagnostic Pathology

Figure 7

From: Dramatic early event in chronic allograft nephropathy: increased but not decreased expression of MMP-9 gene

Figure 7

The potential role of MMP in earlier stage of CAN. A The correlation between the immunostaining of MMP-9 in tubulointerstitium and the quantity of interstitial mononuclear cells in allografts. The immunostaining of MMP-9 in tubulointerstitium was correlated to the quantity of interstitial mononuclear cells in allografts (P < 0.05, Spearman correlation coefficient was 0.757). B The correlation between the immunostaining of MMP-9 in arteriolar wall and the quantity of vascular SMCs in allografts. The immunostaining of MMP-9 in arteriolar wall was correlated to the quantity of vascular SMC in allografts (P < 0.05, Spearman correlation coefficient was 0.741). C The correlation between the immunostaining of MMP-9 and TGF-beta1 in the tubulointerstitium of allografts. The immunostaining of MMP-9 and TGF-beta1in tubulointerstitium in allografts have correlation. (P < 0.01, Spearman correlation coefficient was 0.810). D The correlation between the immunostaining of MMP-9 and TGF-beta1 in arteriolar wall of allografts. The immunostaining of MMP-9 and TGF-beta1 in arteriolar wall of allografts have correlation. (P < 0.001, Spearman correlation coefficient was 0.958).

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