Table 3 Summary of Cox regression analysis of overall survival duration of P27 nuclear and cytoplasm expression
Parameter | Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|---|
P | HR | 95% CI | P | HR | 95% CI | |
Gender | ||||||
Male vs. female | 0.485 | 0.488 | 0.665-2.361 | |||
Age | ||||||
≥50 vs. <50 years | 0.787 | 0.073 | 0.620-1.881 | |||
Family tumor history | ||||||
Yes vs. No | 0.349 | 0.877 | 0.000-28.401 | |||
Smoking | ||||||
Yes vs. No | 0.387 | 0.748 | 0.368-1.474 | |||
Chemotherapy | ||||||
Yes vs. No | 0.700 | 1.153 | 0.560-2.372 | |||
Radiotherapy | ||||||
Yes vs. No | 0.005 | 0.369 | 0.184-0.742 | 0.944 | 1.032 | 0.431-2.469 |
T classification | ||||||
T1-T2 vs. T3-T4 | 0.000 | 13.289 | 1.884-8.223 | 0.014 | 6.032 | 1.225-6.067 |
N classification | ||||||
N0-N1 vs. N2--N3 | 0.000 | 2.950 | 1.662.-5.237 | 0.240 | 1.379 | 0.720-3.700 |
M classification | ||||||
M0 vs. M1 | 0.000 | 35.042 | 5.031-24.906 | 0.001 | 10.438 | 1.803-11.112 |
TNM Clinical stage | ||||||
I-II vs. III-IV | 0.000 | 19.386 | 3.592-27.943 | 0.051 | 3.795 | 0.992-14.238 |
P27 expression | ||||||
High expression vs. low expression | 0.030 | 4.724 | 0.290-0.938 | 0.682 | 0.168 | 0.471-1.637 |