A comparative proteomic study identified calreticulin and prohibitin up-regulated in adrenocortical carcinomas

Diagnostic Pathology

Table 3 Association between calreticulin and prohibitin expression status with clinical charateristics in ACC

Clinical characteristics	Total	Calreticulin expression		P	Prohibitin expression		P
		Low (n = 19)	High (n = 20)		Low (n = 18)	High (n = 21)
Age (y, Mean ± SD)		45 ± 17.4	37 ± 14.5	0.129	43 ± 18.6	39 ± 14.4	0.486
Gender
Male	18	8	10	0.621	8	10	0.843
Female	21	11	10		10	11
Tumor location
Left	17	7	10	0.641	7	10	0.150
Right	19	10	9		8	11
Bilateral	3	2	1		3	0
Primary tumor size
< 5.0 cm	5	2	3		1	4
5.0 – 10.0 cm	28	16	12	0.181	14	14	0.454
> 10.0 cm	6	1	5		3	3
ENSAT stage
I- II	20	13	7	0.037	8	12	0.429
III- IV	19	6	13		10	9
Hormonal secretory status
Non-functioning tumor	21	12	9	0.256	11	10	0.399
Functioning tumor	18	7	11		7	11

ISSN: 1746-1596