Table 1 Association between miR-224 expression and different clinicopathological features of human cervical cancers
Clinicopathological features | No. of cases | miR-224 expression | Â | P |
|---|---|---|---|---|
| Â | Â | High (n, %) | Low (n, %) | Â |
Age | Â | Â | Â | Â |
<50 | 60 | 30 (50.0) | 30 (50.0) | NS |
≥50 | 66 | 36 (54.5) | 30 (45.5) | |
Tumor size (cm) | Â | Â | Â | Â |
<4.0 | 58 | 30 (51.7) | 28 (48.3) | NS |
≥4.0 | 68 | 36 (52.9) | 32 (47.1) | |
Histological grades | Â | Â | Â | Â |
Well differentiated | 28 | 4 (14.3) | 24 (85.7) | 0.03 |
Moderately differentiated | 32 | 12 (37.5) | 20 (62.5) | |
Poorly differentiated | 66 | 50 (75.8) | 16 (24.2) | |
FIGO stage | Â | Â | Â | Â |
Ib~IIa | 64 | 20 (31.3) | 44 (68.7) | 0.02 |
IIb~IIIa | 62 | 46 (74.2) | 16 (25.8) | |
Lymph node metastasis | Â | Â | Â | Â |
No | 79 | 24 (30.4) | 55 (69.6) | 0.008 |
Yes | 47 | 42 (89.4) | 5 (10.6) | |
Vascular invasion | Â | Â | Â | Â |
No | 72 | 20 (27.8) | 52 (72.2) | 0.01 |
Yes | 54 | 46 (85.2) | 8 (14.8) | |
HPV | Â | Â | Â | Â |
(−) | 48 | 10 (20.8) | 38 (79.2) | 0.02 |
(+) | 78 | 56 (71.8) | 22 (28.2) |