Table 5 Comparison of podocin immunostain with other studies
Authors | No. of cases | MCD | FSGS | IgAN | MGN | Henoch Schoenlein purpura nephritis |
|---|---|---|---|---|---|---|
Horinouchi et al (2003)[10] Pediatric and adult | Total | 6 | 19 | 6 | 5 | 6 |
Absent staining | 0 | 7(36.84%) | 0 | 0 | 0 | |
1+ | 0 | 7(36.84%) | 0 | 1(15%) | 0 | |
2+ | 0 | 4(21.05%) | 0 | 19(15%) | 0 | |
3+ | 6(100%) | 1(5.2%) | 6(100%) | 3(60%) | 6(100%) | |
Mao J et al (2006)[11] Pediatric | Total | 9 | - | 6 | - | - |
Podocin fluorescence intensity | Not reduced | Not reduced | ||||
Koop et al (2003)[6] Adult | Total | 10 | 5 | 10 | 1 | |
Podocin IHC intensity quantification by image analysis | Reduced | Reduced | Not altered | Reduced | - | |
Podocin mRNA levels | Increased | Increased | Decreased | Increased | - | |
Guan N et al (2002)[12] Pediatric | Total | 9 | - | 4 | - | - |
Podocin staining intensity | Decreased | Not decreased | Not decreased | - | - | |
Present study | Total | 22 | 21 | 20 | 25 | - |
Absent staining | 0 | 0 | 0 | 0 | - | |
1+ | 0 | 0 | 0 | 0 | - | |
2+ | 6(27.27%) | 7(33.33%) | 3(15%) | 8(32%) | - | |
3+ | 16(72.72%) | 14(66.66%) | 17(85%) | 17(68%) | - |