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Figure 3 | Diagnostic Pathology

Figure 3

From: Systemic IgG4-related disease with extensive peripheral nerve involvement that progressed from localized IgG4-related lymphadenopathy: an autopsy case

Figure 3

Mesentery of the sigmoid colon. A: Macroscopically, patchy fibrotic lesions are seen between fat tissues. B: Fibrosis and dense inflammatory cells are patchily distributed. The inflammatory cells are distributed preferentially around the peripheral nerves (arrowhead). C: Obliterative phlebitis and organization of the accompanying artery are seen. D-F: Immunostaining for IgG (E) and IgG4 (F) in the peripheral nerves. The IgG4+/IgG+ cell ratio is more than 40%.

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